Latest News Archive

Please select Category, Year, and then Month to display items
Years
2017 2018 2019 2020
Previous Archive
18 April 2019 | Story Rulanzen Martin

The Institute for Reconciliation and Social Justice IRSJ) has initiated a Social Justice Week at the University of the Free State (UFS), which started on Friday 12 April  until Wednesday 17 April 2019. 

Ten key events took place during the week. It ranged from dialogues, workshops, talk shows, debates, and interactive displays and events on issues of multilingualism and diversity, social innovation, engaged scholarship, the Fourth Industrial Revolution, gender sensitisation, sexual consent, sexual preparedness, universal access, disability, anti-discrimination, and security.

There was also a round-table discussion on 17 April 2019 with various UFS stakeholders on off-campus student security as well as an inter-institutional discussion on the same topic. The UFS Debating Society will take on the topic of the UFS Language Policy, while Olga Barends from the Free State Centre for Human Rights will host a dialogue on sexual consent.

The IRSJ has also designed and implemented SOJO-VATION: Social Innovation/ Social Change, which strives to create a foundational platform where ideas of social justice, innovation, and engaged scholarship at the UFS and in society can be hosted. SOJO-VATION partners with the Office for Student Leadership, Development, and Community Engagement.

The collaborating partners for the Social Justice Week includes various UFS stakeholders such as the Sasol library, the Gender and Sexual Equity Office, UFS Protection Services, the Free State Centre for Human Rights, the Student Representative Council (SRC), the Office for Student Leadership Development, Kovsie Innovation, GALA, the FFree State Centre for Human Rights, SRC Associations, the Office for Student Governance, Kovsie Innovate, Start-Up-Grind, EVC, EBL, Community Engagement, the Institutional Transformation Plan (ITP) Dialogues Office, Residence Dialogues, UFS Debating Society, Debate Afrika!, the Center for Universal Access and Disability Support (CUADS), and the Gateway Office. 

News Archive

Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept