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29 January 2019 | Story Xolisa Mnukwa | Photo Anja Aucamp
Prof Francis Petersen speech
“We can create an institution that operates and lives in the times of embracing and celebrating diversity, inclusivity, and academic excellence by ensuring that students own their time at university,” said Prof Francis Petersen.

25 January 2019 marked the official welcoming of the University of the Free State’s (UFS) first-year students, as they moved into their respective residences and were warmly welcomed on the UFS Bloemfontein Campus. This day also marked the start of the registration process for first-year students.

According to first-year Psychology student Keisha Claasen, who moved into her residence earlier on 25 January, her first experience of the UFS was daunting but exciting, as she had never been in a similar environment. According to Given Gwerera, who dropped his son off at the Karee residence earlier the day, “the UFS is an institution with great culture and an overall good academic record.” He further explained that he trusts his son to make full use of the opportunities presented to him, as he has a cool head on his shoulders.

On the evening of 25 January, an eager group of millennials, joined by their parents, took the first sip from their cup of varsity life as they assembled on the Red Square of the Bloemfontein Campus to meet the Rector and Vice-Chancellor, Prof Francis Petersen, members of Rectorate, the deans of all faculties, and the Student Representative Council (SRC) of the UFS.

“2019 will be a year of continued change; the UFS is thrilled about the prospect of bringing about opportunities for adaptation and realignment to the future,” said Prof Francis Petersen.

He further explained that the university prides itself in moulding its students into well-rounded individuals who will develop into globally competitive graduates as required in a diversity of landscapes. Prof Petersen urged first-years to remain open to the technological developments that go with globalisation, because of its permanent effects on society today.

First-years were further advised to take advantage of the rich pool of academic research and knowledge that is characteristic of the university and is piloted by UFS scholars, by engaging with and learning from them.

The inspiring night concluded on a colourful note, as the audience enjoyed an artistic laser show in front of the Main Building. Caption:

“UFS academics conduct research that forces the world to take note,” said Prof Francis Petersen at the official first-year welcoming ceremony on the UFS Bloemfontein Campus.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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