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20 August 2020 | Story Andre Damons | Photo Barend Nagel
Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), has been appointed as the chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), will lead Africa’s fight against the COVID-19 pandemic with his appointment as chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Matsabisa has been chosen over 25 other experts from 27 African countries to head this expert committee tasked with setting up research and clinical trials for COVID-19 and beyond. The committee is also supported by the African Union (AU), the Centers for Disease Control and Prevention (CDC – Africa), and the European and Developing Countries Clinical Trials Partnership (EDCTP).

This committee was established by the WHO and the Africa CDC on 22 July with the aim of providing independent scientific advice and support to countries on the safety, efficacy, and quality of traditional medicine therapies. It is also an effort to enhance research and development of traditional medicines for COVID-19 in Africa.

Looking forward

“This is a huge continental and global responsibility being laid on my shoulders as a chairperson.  I have to keep the committee together and ensure that it delivers on its set mandate and terms of reference.  I need to ensure that the committee helps the continent and region to get the scientific and legislative aspects on traditional medicine development on track.”  

“I have taken this position and responsibility, knowing quite well what it entails. I want to do this for the continent and for the sake of good science of all traditional healers and consumers of traditional medicines on the continent and beyond,” says Prof Matsabisa.

According to Prof Matsabisa, he is looking forward to working with a team of dedicated experts from 27 countries in the African region, and being of help to countries that need assistance with clinical trials, including preclinical work to move to clinical research.

Prof Matsabisa says he is also looking forward to countries asking South Africa to be part of their multi-centre studies in clinical trials for traditional medicines, and to help set up clinical trial teams that include Western-trained clinicians to get into traditional medicine studies. 

The work of the committee

According to Prof Matsabisa, his new position took effect the same day as his appointment and will run as long as COVID-19 is part of our daily lives and even beyond. It entails supporting member states to implement the WHO master plan for clinical trial protocols in order to generate credible data for COVID-19 results, based on traditional medicines. The committee will also coordinate support to member states in the African region to collaborate on clinical trials of traditional medicine-based therapies – elevating standards by pooling expertise in multicentre studies, as well as complying with GCP and good participatory practice guidelines for trials of emerging and re-emerging pathogens.
“The committee will also advise on strengthening the capacity of national medicine regulatory authorities to accelerate the issuance of marketing authorisations for traditional medicine products that have been well researched for safety, efficacy, and quality, as well as to expedite the approval of clinical trials on traditional medicines. This will help to meet the national registration criteria and the WHO norms and standards of quality, safety, and efficacy for the management of COVID-19 and others.”

“It will also provide independent scientific advice to the WHO and other partners regarding policies, strategies, and plans for integrating traditional medicines into COVID-19 responses and health systems,” explains Prof Matsabisa. 

Aiming for the top spot 

Prof Matsabisa has been described as having the third highest research output – something he is not satisfied with. 
“I was disappointed that only one point separated me from the second place. I will push for first place as this is my ultimate aim. My motivation for this is simple – I like what I am doing, I do not take it as a job but do it because I love research.”  

“I always like to tell students that we should be proud to one day see products in the shops that we can relate to and to which we have contributed or that we have made.   This is what drives me and my staff.  I have a beautiful team of students, staff, and postdoctoral fellows who share my vision of research.  We all have a shared vision and strive to be relevant at all times in science research, development, and teaching.”

• Prof Matsabisa was recently part of a national conference with the theme: Harnessing science, technology, and innovation in response to COVID-19: A national and international effort. The conference was hosted by Dr Blade Nzimande, Minister of Higher Education, Science and Innovation, with Pres Cyril Ramaphosa, Dr Zweli Mkhize, Minister of Health, Ebrahim Patel, Minister of Trade, Industry and Competition, Prof Sarah Anyang Agbor, African Union Commissioner for Human Resources, Science and Technology, and Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organisation, in attendance. 

News Archive

Early nutrition impacts on burden of disease
2017-11-15


 Description: Corinna Walsh read more Tags: Corinna Walsh read more

Prof Corinna Walsh during her inaugural lecture on ‘Nutrition in Transition’.
Photo: Stephen Collett 

“The first 1 000 days, from conception to two years, is a critical time to ensure that the early environment is optimal to guarantee the best outcomes,” Prof Corinna Walsh, Professor in the Department of Nutrition and Dietetics at the University of Free State (UFS), said. She delivered her inaugural lecture on Nutrition in Transition on 30 October 2017. 

During her lecture, Prof Walsh explained how an unfavourable early environment impacts on the health and well-being of both children and adults. She gave an overview of the prevalence of hunger and food insecurity in the Free State, and described the shift that has occurred from healthier traditional diets to more unhealthy Western diets accompanied by sedentary lifestyles. These patterns are closely linked to the triple burden of malnutrition, including undernutrition, micro-nutrient malnutrition, and obesity. Finally, Prof Walsh highlighted the double burden of disease, focusing on chronic lifestyle diseases on the one hand, and infectious diseases such as HIV/AIDS and TB on the other hand.

“Preparing for this lecture has given me the opportunity to reflect on the almost thirty years of my research journey, a process that I thoroughly enjoyed,” said Prof Walsh.

“It was a privilege to share the work of my research team with fellow colleagues as well as with family and friends,” she said. Prof Walsh is a National Research Foundation C-rated researcher and also served on the Board of the Medical Research Council from 2005 to 2010.

Foundations for health, growth established early
The first 1 000-day window focuses on the time between conception and the second birthday. “This is a critical period for growth and development,” Prof Walsh said. It is a unique period, as the foundations for health, growth, and neuro-development are established. It also focused on the implications of malnutrition, which is the biggest risk factor contributing to the global burden of disease.


Research identifies burden of disease
Her research has made a considerable contribution to identifying the burden of disease in the Free State. “It focuses on both malnutrition and infectious diseases such as HIV and TB on the one hand, and chronic lifestyle diseases such as obesity, diabetes, and hypertension on the other,” she said. The research team have also implemented a number of interventions to address these challenges, including programmes that have assessed the impact of nutrition-education programmes, household food gardens, and nutrition supplementation.

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