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20 August 2020 | Story Andre Damons | Photo Barend Nagel
Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), has been appointed as the chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), will lead Africa’s fight against the COVID-19 pandemic with his appointment as chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Matsabisa has been chosen over 25 other experts from 27 African countries to head this expert committee tasked with setting up research and clinical trials for COVID-19 and beyond. The committee is also supported by the African Union (AU), the Centers for Disease Control and Prevention (CDC – Africa), and the European and Developing Countries Clinical Trials Partnership (EDCTP).

This committee was established by the WHO and the Africa CDC on 22 July with the aim of providing independent scientific advice and support to countries on the safety, efficacy, and quality of traditional medicine therapies. It is also an effort to enhance research and development of traditional medicines for COVID-19 in Africa.

Looking forward

“This is a huge continental and global responsibility being laid on my shoulders as a chairperson.  I have to keep the committee together and ensure that it delivers on its set mandate and terms of reference.  I need to ensure that the committee helps the continent and region to get the scientific and legislative aspects on traditional medicine development on track.”  

“I have taken this position and responsibility, knowing quite well what it entails. I want to do this for the continent and for the sake of good science of all traditional healers and consumers of traditional medicines on the continent and beyond,” says Prof Matsabisa.

According to Prof Matsabisa, he is looking forward to working with a team of dedicated experts from 27 countries in the African region, and being of help to countries that need assistance with clinical trials, including preclinical work to move to clinical research.

Prof Matsabisa says he is also looking forward to countries asking South Africa to be part of their multi-centre studies in clinical trials for traditional medicines, and to help set up clinical trial teams that include Western-trained clinicians to get into traditional medicine studies. 

The work of the committee

According to Prof Matsabisa, his new position took effect the same day as his appointment and will run as long as COVID-19 is part of our daily lives and even beyond. It entails supporting member states to implement the WHO master plan for clinical trial protocols in order to generate credible data for COVID-19 results, based on traditional medicines. The committee will also coordinate support to member states in the African region to collaborate on clinical trials of traditional medicine-based therapies – elevating standards by pooling expertise in multicentre studies, as well as complying with GCP and good participatory practice guidelines for trials of emerging and re-emerging pathogens.
“The committee will also advise on strengthening the capacity of national medicine regulatory authorities to accelerate the issuance of marketing authorisations for traditional medicine products that have been well researched for safety, efficacy, and quality, as well as to expedite the approval of clinical trials on traditional medicines. This will help to meet the national registration criteria and the WHO norms and standards of quality, safety, and efficacy for the management of COVID-19 and others.”

“It will also provide independent scientific advice to the WHO and other partners regarding policies, strategies, and plans for integrating traditional medicines into COVID-19 responses and health systems,” explains Prof Matsabisa. 

Aiming for the top spot 

Prof Matsabisa has been described as having the third highest research output – something he is not satisfied with. 
“I was disappointed that only one point separated me from the second place. I will push for first place as this is my ultimate aim. My motivation for this is simple – I like what I am doing, I do not take it as a job but do it because I love research.”  

“I always like to tell students that we should be proud to one day see products in the shops that we can relate to and to which we have contributed or that we have made.   This is what drives me and my staff.  I have a beautiful team of students, staff, and postdoctoral fellows who share my vision of research.  We all have a shared vision and strive to be relevant at all times in science research, development, and teaching.”

• Prof Matsabisa was recently part of a national conference with the theme: Harnessing science, technology, and innovation in response to COVID-19: A national and international effort. The conference was hosted by Dr Blade Nzimande, Minister of Higher Education, Science and Innovation, with Pres Cyril Ramaphosa, Dr Zweli Mkhize, Minister of Health, Ebrahim Patel, Minister of Trade, Industry and Competition, Prof Sarah Anyang Agbor, African Union Commissioner for Human Resources, Science and Technology, and Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organisation, in attendance. 

News Archive

UFS Cardiovascular Research Centre a South African solution to continental crisis
2015-11-30

From left are: Dr Robert Kleinloog, president of the Society of Cardiothoracic Surgeons of South Africa, Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), Prof Robert Frater after which the Robert W M Frater Cardiovascular Research Centre was named and Prof Francis Smit, head of Cardiothoracic Surgery at the UFS, at the launch of the new centre.
Photo: Johan Roux

“You don’t have to be in New York or any big city in the world to establish a cardiovascular centre that delivers work of world standards. I’ve learned that extraordinary things are achieved by ordinary people who apply themselves accordingly. This research centre is a South African solution to a continental challenge”.

These were the words of Prof Robert Frater at the opening of the new Robert W M Frater Cardiovascular Research Centre in the Department of Cardiothoracic Surgery at the University of the Free State (UFS) School of Medicine.

The centre, one of only two of the kind in the country, will focus on bioengineering and cardiovascular research. It was opened on Wednesday 18 November 2015 in the Francois Retief Building on the Bloemfontein campus.

The centre is named after Prof Robert W.M Frater in recognition of his vast contribution to the UFS. He is internationally recognised for his outstanding academic, clinical, and scientific contributions to cardiac surgery. Prof Frater has also been actively involved in research activities of the Department of Cardiothoracic Surgery for the last 10 years. In 2011, he received an honorary doctorate from the UFS.

Under the leadership of Prof Francis Smit, head of Cardiothoracic Surgery, the department has been described as a dynamic unit at the forefront of meeting the different changes in Southern Africa while maintaining an excellent clinical and academic track record.

At the opening, Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, thanked Prof Frater for his presence at, involvement in, and support of the UFS. “I am looking forward to working in collaboration with the department to make this university a research centre of excellence in the continent”, he said.

The centre has existing endeavours already in operation, including Population projects, Clinical studies, and Clinical pathology, to name three. In collaboration with the Central University of Technology, the University of Stellenbosch, and Charite University of Berlin, among numerous others, the centre will be an appropriate help to an African challenge.

Its introduction promises advanced research outcomes with the potential to make the Department of Cardiothoracic Surgery a world-class competitor.

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