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20 August 2020 | Story Andre Damons | Photo Barend Nagel
Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), has been appointed as the chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Motlalepula Matsabisa, Associate Professor in the Department of Pharmacology at the University of the Free State (UFS), will lead Africa’s fight against the COVID-19 pandemic with his appointment as chairperson of the World Health Organisation’s (WHO) Regional Expert Advisory Committee on Traditional Medicines for COVID-19.

Prof Matsabisa has been chosen over 25 other experts from 27 African countries to head this expert committee tasked with setting up research and clinical trials for COVID-19 and beyond. The committee is also supported by the African Union (AU), the Centers for Disease Control and Prevention (CDC – Africa), and the European and Developing Countries Clinical Trials Partnership (EDCTP).

This committee was established by the WHO and the Africa CDC on 22 July with the aim of providing independent scientific advice and support to countries on the safety, efficacy, and quality of traditional medicine therapies. It is also an effort to enhance research and development of traditional medicines for COVID-19 in Africa.

Looking forward

“This is a huge continental and global responsibility being laid on my shoulders as a chairperson.  I have to keep the committee together and ensure that it delivers on its set mandate and terms of reference.  I need to ensure that the committee helps the continent and region to get the scientific and legislative aspects on traditional medicine development on track.”  

“I have taken this position and responsibility, knowing quite well what it entails. I want to do this for the continent and for the sake of good science of all traditional healers and consumers of traditional medicines on the continent and beyond,” says Prof Matsabisa.

According to Prof Matsabisa, he is looking forward to working with a team of dedicated experts from 27 countries in the African region, and being of help to countries that need assistance with clinical trials, including preclinical work to move to clinical research.

Prof Matsabisa says he is also looking forward to countries asking South Africa to be part of their multi-centre studies in clinical trials for traditional medicines, and to help set up clinical trial teams that include Western-trained clinicians to get into traditional medicine studies. 

The work of the committee

According to Prof Matsabisa, his new position took effect the same day as his appointment and will run as long as COVID-19 is part of our daily lives and even beyond. It entails supporting member states to implement the WHO master plan for clinical trial protocols in order to generate credible data for COVID-19 results, based on traditional medicines. The committee will also coordinate support to member states in the African region to collaborate on clinical trials of traditional medicine-based therapies – elevating standards by pooling expertise in multicentre studies, as well as complying with GCP and good participatory practice guidelines for trials of emerging and re-emerging pathogens.
“The committee will also advise on strengthening the capacity of national medicine regulatory authorities to accelerate the issuance of marketing authorisations for traditional medicine products that have been well researched for safety, efficacy, and quality, as well as to expedite the approval of clinical trials on traditional medicines. This will help to meet the national registration criteria and the WHO norms and standards of quality, safety, and efficacy for the management of COVID-19 and others.”

“It will also provide independent scientific advice to the WHO and other partners regarding policies, strategies, and plans for integrating traditional medicines into COVID-19 responses and health systems,” explains Prof Matsabisa. 

Aiming for the top spot 

Prof Matsabisa has been described as having the third highest research output – something he is not satisfied with. 
“I was disappointed that only one point separated me from the second place. I will push for first place as this is my ultimate aim. My motivation for this is simple – I like what I am doing, I do not take it as a job but do it because I love research.”  

“I always like to tell students that we should be proud to one day see products in the shops that we can relate to and to which we have contributed or that we have made.   This is what drives me and my staff.  I have a beautiful team of students, staff, and postdoctoral fellows who share my vision of research.  We all have a shared vision and strive to be relevant at all times in science research, development, and teaching.”

• Prof Matsabisa was recently part of a national conference with the theme: Harnessing science, technology, and innovation in response to COVID-19: A national and international effort. The conference was hosted by Dr Blade Nzimande, Minister of Higher Education, Science and Innovation, with Pres Cyril Ramaphosa, Dr Zweli Mkhize, Minister of Health, Ebrahim Patel, Minister of Trade, Industry and Competition, Prof Sarah Anyang Agbor, African Union Commissioner for Human Resources, Science and Technology, and Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organisation, in attendance. 

News Archive

Inaugural lecture: World on verge of agricultural revolution
2008-05-19

A changing economic climate and new technology will see to a number of interesting changes in the livestock industry in the next few years. This is according to Prof. Frikkie Neser of the Department of Animal and Wildlife and Grassland Sciences, who delivered his inaugural lecture at the UFS on the subject: “The quest for a superior animal”.

Prof. Neser focused on the future of animal breeding in the next few decades.

He said the world, but especially South Africa, stand on the verge of a revolution in the agriculture sector. The whole production scenario will probably change. The high fuel and food prices are the two biggest factors that will play a role.

“Increasing fuel prices opened the door for the production of bio-fuel. The fuel industry is in direct competition with humans and the livestock industry for the same resource that result in unbelievable high prices for maize, sunflower and soya. These prices can further increase with the worldwide shortage of food,” he said.

More profitable breeds could take the place of existing breeds because of the big increase in input costs, he said. “Selection for more effective, and not maximum production, will became more important.

“There are also indications of pressure on feed lots. If this industry downsizes, it could lead to a total turnaround in the beef industry. The feed lots prefer a later maturing animal that can put on a lot of weight before fat is laid down. If this industry declines, early maturing breeds and some of the synthetic breeds, as well as crossbreeding with early maturing breeds, will play a more prominent role in the meat industry.

“This will also lead to a decline in the total number of animals in order to prevent overgrazing. This can result in an increase in imports from neighbouring countries and especially Brazil, where production costs are much lower.

“One way to increase the profitability of meat production is to utilise niche markets. There is world-wide a shift to more natural products. The demand for grass-fed beef drastically increased. According to research it is healthier than meat from feed lots and usually free of hormones and antibiotics. If factors such as traceability are put in place, this could be a very profitable niche mark for the South African meat industry,” he said.

Prof. Neser also said: “In order for breeding societies to survive they need to increase the number of members and the animals that are being registered. This they do by replacing the word stud with recorded animals. Hereby they open the door for excellent commercial animals to become part of the seed-stock industry. Another benefit is that especially in the smaller breeds more information becomes available, resulting in more accurate breeding values.”

Prof. Frikkie Neser.

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