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Chris Vorster
Chris was on stage in 'Die Hart Verklap' at the Toyota US Woordfees in Stellenbosch recently.

“Difficult and very strange,” is how Chris Vorster, veteran actor and Drama lecturer at the University of the Free State (UFS) describes his role as Bas Koorts in the supernatural thriller Die Spreeus

For Chris, the biggest challenge during the filming of Die Spreeus was to work in front of a green screen. “You never see the monsters and things attacking you, it is only added later on during the editing process,” he said. Therefore, he and his co-actors were expected to use their own imagination “to be frightened, and to duck and dive from something that does not exist.” 

This Afrikaans thriller series has recently been nominated in five categories of the South African Film and Television Awards, including Best Television Drama, Best Cinematography, and Original Sound and Sound Editing. 

Chris was also nominated for a Fiësta award in 2019 for his one-man performance in the theatre production, Die Hart verklap. “It is fantastic to still be recognised for my work,” he said, “but I also have to give recognition to Dion van Niekerk, because without a good director, any actor will be lost.” Van Niekerk also lectures Drama at the UFS.

Being a lecturer broadens his knowledge 

Chris joined the UFS Department of Drama and Theatre Arts in 2015 as lecturer in the programme for Film en Visual Media. “Everything I learn in the industry I apply as lecturer, and research and teaching feed more knowledge on acting, directing, and especially writing,” he said. After five years, being involved with the UFS Department of Drama is still exciting to him. “This is where both lecturers and students get encouraged to do more than just breathing.” 

With his busy schedule of teaching and acting, it remains important to him that South Africans are still able to tell stories – “in any language”. He considers it a privilege for anyone to work in their mother tongue. This is also why the symbiosis between his work as actor and lecturer is so appealing.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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