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30 October 2020 | Story Leonie Bolleurs

The Department of Science and Technology has extended two of the National Research Foundation’s SARChI research chairs at the University of the Free State (UFS). 

The Research Chair in Diseases and Quality of Field Crops, together with the Research Chair in Vector-borne and Zoonotic Pathogens, have both been extended for another five years. 

Prof Maryke Labuschagne, currently Professor of Plant Breeding in the Department of Plant Sciences, is leading the chair on Diseases and Quality of Field Crops.

The Chair on Vector-borne and Zoonotic Pathogens is headed by Prof Felicity Burt from the Division of Virology in the Faculty of Health Sciences.

Prof Corli Witthuhn, Vice-Rector: Research, says it was the hard work and commitment of Profs Labuschagne and Burt that resulted in the extension of the SARChI research chairs. “They have excelled in terms of student supervision and publications in high-impact international journals.  They also serve as mentors for young academics, postdoctoral fellows, and colleagues through their passion for their different fields of interest.”

Prof Witthuhn believes that this extension of the two SARChI chairs speaks of the progress that the UFS has made in terms of developing itself as a research-led university. “We are proud of the two senior academics for their supervision, mentorship, and leadership and their contribution to building our reputation,” she says. 

Diseases and Quality of Field Crops

The focus of the research chair in Diseases and Quality of Field Crops is on advancing food security and nutrition in Africa and contributing to poverty reduction and achieving sustainability goals. 

Prof Labuschagne says despite recent advances, the headlines regarding hunger and food security remain alarming: one in nine people on earth will go to bed hungry every night. Globally, 800 million people do not have enough to eat to be healthy, and a third of all deaths among children under five in developing countries are linked to undernourishment. 

She believes the uniqueness and strength of the research chair lies in a two-pronged approach, namely the breeding of cereal crops for resistance to fungal diseases, and improving the quality of crops for processing and consumption, thus making an impact on food security in South Africa and the rest of Africa through this collaborative effort. 

She is confident that the extension of the research chair will allow them to continue and to expand their research, “which has built up a lot of momentum”.

Besides the 12 PhD and 8 MSc degrees they delivered in the first five years, they also contributed significant research outputs and cultivar releases. She adds that they would like to expand on the significant international collaboration they have established. 

Vector-borne and Zoonotic Pathogens

According to Prof Burt, the SARChI chair in Vector-borne and Zoonotic Pathogens builds on existing research strengths at the UFS and aims to contribute towards identifying and investigating medically significant arboviruses and zoonotic viruses in the country.
 
“To date, the research chair has facilitated progress towards establishing serosurveillance studies for various vector-borne viruses, specifically Crimean-Congo haemorrhagic fever virus, a tick-borne and zoonotic virus that causes severe disease with fatalities.”

The team of researchers operating within this research chair is currently also performing studies to determine the seroprevalence of severe acute respiratory coronavirus 2 (SARS-CoV-2) in the Free State.

Prof Burt has always taken the importance of community engagement into account, and with the current pandemic, she believes that it is now more important than ever to increase public awareness of zoonotic diseases.

She emphasises that the majority of new and emerging viruses are zoonotic in origin and that the current SARS-CoV-2 pandemic highlights the impact of an emerging zoonotic pathogen on society. Therefore, she feels that it is important to build capacity in this field and to focus research efforts on identifying and understanding where these pathogens cycle in nature, the potential for spill-over to humans, and what the drivers are for the emergence of these pathogens.

Prof Burt trusts that the renewal of the research chair will allow them to take advantage of the new biosafety laboratory that the UFS has invested in. “This will permit us to research pathogens that were previously excluded from our programme due to biosafety considerations.  The chair will furthermore contribute towards enhancing, strengthening, and developing research and knowledge in the field of epidemiology and pathogenesis of vector-borne and zoonotic viruses,” she says. 

News Archive

Research into surrogate milk important to wildlife conservation
2017-05-08

Description: Prof Garry Osthoff  Tags: Prof Garry Osthoff

Prof Gary Osthoff from the UFS Department of
Microbial, Biochemical and Food Biotechnology,
will soon work on a milk formula for elephants.
Photo: Supplied

Research is being done at the University of the Free State (UFS) to analyse and synthetically imitate the unique milk of various wildlife species. This research is not only of scientific value, but also serves the conservation of South Africa’s wildlife species. At the forefront of this research is Prof Garry Osthoff from the Department of Microbial, Biochemical and Food Biotechnology.

Orphaned rhino calf pulled through with surrogate milk

“There is still a lot of research to be done. Naturally the research is of scientific importance, but with surrogate milk having the same composition as the mother’s milk of a specific species, orphaned calves or cubs of that species could be pulled through during a difficult time of weaning. Bearing in mind that exotic animals fetch thousands and even millions of rands at auctions, it goes without saying a game farmer will do everything possible to provide only the best nourishment to such an orphaned animal. In such a case, synthetically-manufactured milk would be the right choice,” says Prof Osthoff.

The fruits of his research were recently demonstrated in Germany when a rhino calf was left orphaned in the Leipzig Zoo. Prof Osthoff’s article: “Milk composition of a free-ranging white rhinoceros during late lactation” was used as a directive for applying surrogate milk for horse foals (which is already commercially available), since the composition of horse and rhino milk largely corresponds. The surrogate milk was used with great success and the rhino calf is flourishing. He mentions that such an orphan is often given the wrong nourishment with the best intentions, resulting in the starvation of the animal despite the amount of cow’s milk it devours.

With surrogate milk having the same
composition as the mother’s milk of a
specific species, orphaned calves or
cubs of that species could be pulled
through during the difficult time
of weaning.

Milk formula for baby elephants in the pipeline
With baby elephants left orphaned due to the increase in elephant poaching for their ivory, several attempts have been made to create a milk formula in order to feed these elephants. To date, many elephants have died in captivity from side effects such as diarrhoea as a result of the surrogate formula which they were fed.

Prof Osthoff recently received a consignment of frozen milk which he, together with researchers from Zimbabwe, will use to work on a milk formula for elephants. They are studying the milk in a full lactation period of two years. During lactation, the composition of the milk changes to such an extent that a single surrogate formula will not be sufficient. Four different formulas should probably be designed.

Prof Osthoff says that of the different species he has researched, elephants are the most interesting and deviate most from the known species.

Although his research to develop surrogate milk is adding much value to the wildlife industry, and although he finds this part of his work very exciting, his research focus is on food science and nutrition. “What is currently authentic in milk research is the study of the fat globules with content, the structure and composition of the casein micelle, and the prebiotic sugars. The knowledge which is gained helps to improve the processing, development of new food products, and development of food products for health purposes,” says Prof Osthoff.

 

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