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08 February 2021 | Story André Damons | Photo Charl Devenish
Prof Mamello Sekhoacha, Associate Professor from the Department of Pharmacology in the Faculty of Health Sciences, was appointed by Dr Zweli Mkhize, Minister of Health, as the new chairperson of the National Health Research Ethics Council of South Africa (NHREC).

A researcher in the field of drug discovery and development at the University of the Free State (UFS) has been appointed by Dr Zweli Mkhize, Minister of Health, as the new chairperson of the National Health Research Ethics Council of South Africa (NHREC).

Prof Mamello Sekhoacha, Associate Professor from the Department of Pharmacology in the Faculty of Health Sciences, was appointed as a member of the NHREC council in 2013, and later became the chairperson of the NHREC’s Norms and Standards Committee responsible for developing and revising guidelines for health research. Prof Sekhoacha was appointed deputy chairperson of the council in 2018 and has played an integral part in setting ethical standards for conducting health research in the country.

 Responsibilities of the NHREC

The NHREC is the national statutory body responsible for the governance and advancement of health research ethics in South Africa. Some of the responsibilities of the council are to set ethical norms and standards for health research by developing and revising the guidelines pertaining to health research; to promote and monitor compliance with existing regulations by health research ethics committees; and to build capacity in research ethics committees through robust registration and audit processes.

These responsibilities of the NHREC rest on the need to ensure ethical integrity in research involving human participants and animal subjects, and that research is based on sound scientific and ethical principles.

“It is an honour for me to serve on the NHREC for the third term. The NHREC has achieved remarkable outputs over the past three years, and I believe, given the current composition of the council members, this momentum will not be lost. One of the goals of the NHREC is to further broaden the scope of the ethics in health research guidelines from ‘biomedical research’ to ‘health-related research’ to ensure that adequate guidance is provided for those in health-related disciplines, as a response to the changing environment of research involving humans and the broader meaning of health research.” 

“We need more comprehensive guidelines with nuanced commentaries to indicate how the ethical principles that emanated from biomedical research involving humans, could be effectively implemented in other disciplines of health-related research,” says Prof Sekhoacha. 

Global paradigm shift in role and integration of ethics in health research

Having been a council member since 2013, Prof Sekhoacha, whose training spans from pre-clinical laboratory experimentation, the use of animals in research, clinical trials, and working with indigenous communities, says there is a global paradigm shift in the role and integration of ethics in health research in almost all aspects of research, with an increased emphasis on the scientific and social value of research: the prospect of generating the knowledge in a manner that protects and promotes people's health. Considerations of the NHREC go beyond developing ethical guidelines or ensuring the efficient functioning of the ethics committees, to raising awareness among research institutions and researchers to continually promote ethically sound research conduct. 

The subject of ethics in health research is pivotal and reflective of the values of both the institution and the country at large. 

UFS uses Prof Sekhoacha’s expertise on ethics

Prof Sekhoacha is also a co-opted advisory member in the Senate Research Ethics Committee of the UFS and facilitates workshops and seminars on research ethics offered by the Postgraduate School.

Prof Corli Witthuhn, Vice-Rector: Research and Internationalisation, says it is a great honour for the UFS that Prof Sekhoacha has been elected chair of the NHREC.  “The NHREC governs the research ethics processes in South Africa, and it is strategically important for the UFS to now have one of our own academics play such a nationally important role.  We have been using Prof Sekhoacha’s expertise on issues of ethics and we are looking forward to working with her to continue to better our own ethics processes.”

News Archive

Nobel Laureate for Chemistry to visit UFS
2017-10-28

Description: Prof Levitt read more Tags: Prof Levitt read more

Prof Michael Levitt will be hosted by the UFS from
14 to 16 November 2017, where he will present the
first lecture in the Vice-Chancellor’s
Prestige Lecture Series.
Photo: Supplied

It is a great honour for the University of the Free State (UFS) to host Prof Michael Levitt, recipient of the 2013 Nobel Prize for Chemistry, which he shares with Marti Karplus and Arieh Warshel.

The trio received the Nobel Prize for their development of multiscale models used for complex chemical systems. “Being awarded the Nobel Prize is a unique and marvellous experience that no one can prepare for or could in any way know what to except,” said Prof Levitt during his 2013 Nobel Lecture at the Stanford University School of Medicine.

First lecture in Vice-Chancellor’s lecture series

The South African-born Nobel Laureate and Academy of Science of South Africa (ASSAf) Visiting Scholar will present the first lecture, Birth and Future of Multiscale Modelling of Macromolecules, in the Vice-Chancellors Prestige Lecture Series at the UFS on 14 November 2017. Prof Levitt is well-known for developing approaches which predict macromolecular structures.

He is one of many distinguished academics invited annually by ASSAf to deliver lectures as part of the Distinguished Visiting Scholars’ Programme, presented by ASSAf at universities across the country.

Pioneer in research of molecular dynamics

Prof Levitt is a biophysicist and a professor of Biology at Stanford University. He was one of the earliest researchers to conduct research on molecular dynamics stimulations of DNA and proteins. “My post-prize ambitions are twofold and probably inconsistent: (1) Work single-mindedly as I did in the mid-1970s on hard problems, and (2) Help today’s young scientists gain the recognition and independence which my generation enjoyed,” said Prof Levitt.

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