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Alistair Naidoo, second-year master’s student in Conservation Genetics and full-time technician in the Department of Genetics; Prof Paul Grobler, Head of the Department of Genetics; Prof Gordon Luikart; and Hannah Janse van Vuuren, third-year master’s student in Conservation Genetics.

It is an important and exciting time to be doing research in conservation genetics. This is according to Prof Gordon Luikart, Professor of Conservation Ecology and Genetics at the Flathead Lake Bio Station at the University of Montana in the United States. 

Prof Luikart, whose primary research focus is the application of genetics to the conservation of natural and managed populations, recently delivered a lecture, The Expanding Role of Genetics/omics in Wildlife Research and Conservation, on the Bloemfontein Campus of the University of the Free State (UFS). The lecture, hosted by the Department of Genetics, was attended by a group of students and lecturers in conservation and a number of related fields. 

He is one of the leading scientists in the field of conservation genetics, including integration of genomics in conservation projects. He is also co-author of the textbook Conservation and the Genomics of populations – the current prescribed textbook for GENE3744.

Species threatened with extinction

In 2008, the International Union for Conservation of Nature (IUCN) stated that approximately 10-20% of all vertebrate and plant species are threatened with extinction over the next few decades. In 1984, American biologist Edward O Wilson also said that it will take millions of years to correct the ongoing loss of genetics and species diversity caused by the destruction of natural habitats. “This is the folly our descendants are least likely to forgive us.”

Prof Luikart is of the opinion that genetics has enormous potential to help manage wildlife and prevent extirpation. “My research works to realise this potential and help wildlife managers conserve populations and ecosystems,” he says. 

Conservation managers and biologists have understood the risks of inbreeding for more than 100 years. In his lecture, one of the aspects of genetic conservation he focused on, was the negative effects of inbreeding and how this can be reversed using genetic rescue. 

With the genetic rescue study, they found that the gene flow into recently isolated populations can increase individual fitness and population growth. He proposed that conservation managers should consider genetic principles and rescue as practical and important tools. 

Prof Luikart also provided a list of information that can be retrieved from molecular genetic data to help conservation managers. This includes intel on census and effective population size, gene flow and dispersal, local adaptation and selection, forensics, genetic identification and law enforcement, and disease ecology and transmission. 

Non-invasive genetic monitoring

In terms of detecting gene flow, he focused on a study about non-invasive genetic monitoring that was conducted in the Yellowstone Park. Prof Luikart and a group of students collected the shed hair and faeces of the grizzly bear, obtained from trees and hair traps, which were used as a source of DNA. 

They established, for instance, that inbreeding depression is more common and stronger than previously thought in natural populations. Genetic monitoring, using non-invasive methods as described, has been found to be an effective tool that conservation managers should consider for detecting inbreeding and loss of genome-wide variation.

His research on the bighorn sheep, the alpine ibex, and the black bear informed most of the findings he discussed during his lecture.

News Archive

UFS scientists involved in groundbreaking research to protect rhino horns
2010-07-27

Pictured from the left are: Prof. Paul Grobler (UFS), Prof. Antoinette Kotze (NZG) and Ms. Karen Ehlers (UFS).
Photo: Supplied

Scientists at the University of the Free State (UFS) are involved in a research study that will help to trace the source of any southern white rhino product to a specific geographic location.

This is an initiative of the National Zoological Gardens of South Africa (NZG).

Prof. Paul Grobler, who is heading the project in the Department of Genetics at the UFS, said that the research might even allow the identification of the individual animal from which a product was derived. This would allow law enforcement agencies not only to determine with certainty whether rhino horn, traded illegally on the international black market, had its origin in South Africa, but also from which region of South Africa the product came.

This additional knowledge is expected to have a major impact on the illicit trade in rhino horn and provide a potent legal club to get at rhino horn smugglers and traders.

The full research team consists of Prof. Grobler; Christiaan Labuschagne, a Ph.D. student at the UFS; Prof. Antoinette Kotze from the NZG, who is also an affiliated professor at the UFS; and Dr Desire Dalton, also from the NZG.

The team’s research involves the identification of small differences in the genetic code among white rhino populations in different regions of South Africa. The genetic code of every species is unique, and is composed of a sequence of the four nucleotide bases G, A, T and C that are inherited from one generation to the next. When one nucleotide base is changed or mutated in an individual, this mutated base is also inherited by the individual's progeny.

If, after many generations, this changed base is present in at least 1% of the individuals of a group, it is described as a single nucleotide polymorphism (SNP), pronounced "snip". Breeding populations that are geographically and reproductively isolated often contain different patterns of such SNPs, which act as a unique genetic signature for each population.

The team is assembling a detailed list of all SNPs found in white rhinos from different regions in South Africa. The work is done in collaboration with the Pretoria-based company, Inqaba Biotech, who is performing the nucleotide sequencing that is required for the identification of the SNPs.

Financial support for the project is provided by the Advanced Biomolecular Research cluster at the UFS.

The southern white rhino was once thought to be extinct, but in a conservation success story the species was boosted from an initial population of about 100 individuals located in KwaZulu-Natal at the end of the 19th century, to the present population of about 15 000 individuals. The southern white rhino is still, however, listed as “near threatened” by the World Wildlife Fund (WWF).

Media Release:
Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za 
27 July 2010



 

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