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30 August 2022 | Story André Damons | Photo André Damons
UFS Nuclear Medicine
The team of doctors in the Department of Nuclear Medicine behind the success story are, from the left (standing): Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer; Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS; and Dr Walter Endres, nuclear medicine registrar. In front is Dr Tebatso Tebeila, nuclear medicine registrar.

The University of the Free State (UFS) Department of Nuclear Medicine is proud to announce the successful treatment outcome of a patient with metastatic castrate-resistant prostate cancer (MCRPC) – an advanced stage of prostate cancer – by using Lutetium 177 PSMA (Lu-177 PSMA) therapy. This was initially a case of advanced stage prostate cancer, which had failed first-line chemotherapy, leaving little or no other treatment options.

This is a proud and happy moment for the department and the UFS, which started this treatment just over a year ago. The university and the Free State province are now joining other South African medical universities, such as the University of Pretoria, and other provinces in using this method to treat MCRPC patients. Lutetium 177 PSMA (Lu-177 PSMA) therapy is used on MCRPC patients who are not eligible for chemotherapy or have failed first- or second-line chemotherapy.

Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, says the department is proud to be able to offer this treatment option to some of these patients. “It is a big win for the Free State and our oncology patients to be able to offer these expert services.” The UFS and Universitas Academic Hospital have now been able to join up with other academic institutions and hospitals in other provinces to offer these services. So far, three patients have been offered this therapeutic option, with the third patient currently undergoing his treatment.

Funds and equipment for proper treatment selection are needed

The expertise is no longer an issue for the UFS, as Dr Osayande Evbuomwan, nuclear medicine specialist and consultant, was trained and exposed to this therapy at the University of the Witwatersrand during his training as a nuclear medicine resident. Current registrars in the Department of Nuclear Medicine at the UFS are also being trained in the application of this treatment modality. However, proper patient selection is key in the management of these cases with Lu 177 PSMA. Without a PET/CT camera, it is challenging to appropriately select the patients who are most likely to respond to this therapy. This is an example of how PET/CT is crucial in the management and monitoring of oncology patients.

Both Drs Engelbrecht and Evbuomwan hope that the training of more registrars will increase their department’s capacity to treat more patients. They also hope that funds will be made available to acquire a much-needed PET/CT camera, which will greatly assist them in identifying the correct patients in need of this treatment. 

With the permission of the patient, the images above show the dramatic treatment response following Lu-177 PSMA therapy. The images on the left show widespread bone disease from the prostate cancer, including the skull. The images on the right show the dramatic response after completing four cycles of Lu 177 PSMA, with the normal excretion of the radiotracer seen in the liver, kidneys, and bladder.


Treatment puts the department, UFS, and hospital on the map

According to Dr Evbuomwan, the ability to administer this treatment puts the department, the UFS, and the hospital on the map, alongside other top universities within and outside the country. Says he: “It also creates an avenue for us to gather data for training, research purposes, and publications. We are now able to offer a promising, safe, and highly efficacious therapy for patients with MCRPC in the Free State. Some of these patients will no longer have to travel to other provinces to receive this treatment.”


“We are also well aware that not every patient will respond this way; however, proper patient selection is key in identifying responders – an area that is still being researched. We also do not know how long these patients will have their disease under control after the treatment. Nuclear medicine’s greatest cancer therapy success story is the treatment of well-differentiated thyroid cancer with radioactive iodine.” 

“After treatment, most of these patients remain cancer-free for a very long period of time, if not for life. With continuing research in the field of MCRPC radioligand therapy, we aim to improve the treatment modality, hopefully getting it to the success level of thyroid cancer therapy.”

 

News Archive

UFS School of Nursing opens new frontiers at 40
2009-11-16

The opening of the virtual facility of the School of Nursing at the University of the Free State (UFS) and a gala dinner to celebrate the School’s 40th year of existence took place on the Main Campus in Bloemfontein this week. At the opening were, among others, from the left: Prof. Jonathan Jansen, Rector and Vice-Chancellor of the UFS; Dr Oluseyi Oyedele and Ms Viona Munjeri, both from The Atlantic Philanthropies; and Prof. Anita van der Merwe, Head of the School of Nursing at the UFS.
Photo: Leatitia Pienaar

All eyes in the nursing profession in South Africa were turned to the University of the Free State (UFS) when the School of Nursing opened a state-of-the-art virtual health training and learning facility and celebrated its 40th year of existence with a gala dinner on the Main Campus in Bloemfontein this week.

The lustrous events were attended by dignitaries from all spheres of the health-care fraternity in South Africa.

The new virtual facility, The Space, is made possible by a grant of R16 million from The Atlantic Philanthropies and R1 million from the UFS. The Atlantic Philanthropies organisation is an international philanthropic organisation that is going to inject R70 million into nursing in South African over the next four years. The initiative will enhance nursing education and step up the quality of health-care delivery in South Africa. Four major grants were made to universities in South Africa, of which the UFS is one.

With the facility at the UFS School of Nursing, nursing education is propelled into the future. Prof. Anita van der Merwe, Head of the School of Nursing, says, “The virtual learning facility is a very new way of thinking and teaching. At the moment, theory and practice are separated, as theory is often taught in the mornings, followed by practical settings later in the day. Learner nurses then also go to clinical facilities for their practicals where the quality of care is declining and human resources are a problem.

“We believe that with new technologies such as e-learning and high-tech computer-mediated equipment we can use the ‘virtual world’ to bridge the theory-practice gap in the same location.”

Prof. Van der Merwe says the project is essentially about transformation: taking a stand against stagnation in nursing education and practice and daring to be different.

In the new virtual facility nurses will have the best of three worlds – the expertise of the facilitator/educator, simulation technology, and a vast selection of on-line and off-line software, exposing them to blogs, broadcasting and enhancing computer literacy. This will attract both the new “millennial” generation, which tends to be technologically competent, as well as the older learner because of the unthreatening learning environment.

The core space will accommodate 40 to 60 students and is designed to encourage informal, collaborative learning and practice simultaneously. It will have a demarcated area for “patients” (such as advanced adult and baby patient simulators) and a “clinic space” allowing for role play.

At the gala dinner, Prof. Jonathan Jansen, Rector and Vice-Chancellor of the UFS commended nurses in South Africa for their caring role, but also expressed his concern that South African has lost its deep sense of care. South Africa is at a critical point and the country can be changed if a deep sense of care can be embedded again.

About forty nursing educators from all over South Africa attended an exploratory workshop in the facility today and the last meeting of the Forum of University Deans in South Africa (FUNDISA) also coincided with the festivities at the School of Nursing.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
13 November 2009
 

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