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30 August 2022 | Story André Damons | Photo André Damons
UFS Nuclear Medicine
The team of doctors in the Department of Nuclear Medicine behind the success story are, from the left (standing): Dr Osayande Evbuomwan, nuclear medicine specialist and Senior Lecturer; Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS; and Dr Walter Endres, nuclear medicine registrar. In front is Dr Tebatso Tebeila, nuclear medicine registrar.

The University of the Free State (UFS) Department of Nuclear Medicine is proud to announce the successful treatment outcome of a patient with metastatic castrate-resistant prostate cancer (MCRPC) – an advanced stage of prostate cancer – by using Lutetium 177 PSMA (Lu-177 PSMA) therapy. This was initially a case of advanced stage prostate cancer, which had failed first-line chemotherapy, leaving little or no other treatment options.

This is a proud and happy moment for the department and the UFS, which started this treatment just over a year ago. The university and the Free State province are now joining other South African medical universities, such as the University of Pretoria, and other provinces in using this method to treat MCRPC patients. Lutetium 177 PSMA (Lu-177 PSMA) therapy is used on MCRPC patients who are not eligible for chemotherapy or have failed first- or second-line chemotherapy.

Dr Gerrit Engelbrecht, Clinical Head of the Department of Nuclear Medicine at the UFS, says the department is proud to be able to offer this treatment option to some of these patients. “It is a big win for the Free State and our oncology patients to be able to offer these expert services.” The UFS and Universitas Academic Hospital have now been able to join up with other academic institutions and hospitals in other provinces to offer these services. So far, three patients have been offered this therapeutic option, with the third patient currently undergoing his treatment.

Funds and equipment for proper treatment selection are needed

The expertise is no longer an issue for the UFS, as Dr Osayande Evbuomwan, nuclear medicine specialist and consultant, was trained and exposed to this therapy at the University of the Witwatersrand during his training as a nuclear medicine resident. Current registrars in the Department of Nuclear Medicine at the UFS are also being trained in the application of this treatment modality. However, proper patient selection is key in the management of these cases with Lu 177 PSMA. Without a PET/CT camera, it is challenging to appropriately select the patients who are most likely to respond to this therapy. This is an example of how PET/CT is crucial in the management and monitoring of oncology patients.

Both Drs Engelbrecht and Evbuomwan hope that the training of more registrars will increase their department’s capacity to treat more patients. They also hope that funds will be made available to acquire a much-needed PET/CT camera, which will greatly assist them in identifying the correct patients in need of this treatment. 

With the permission of the patient, the images above show the dramatic treatment response following Lu-177 PSMA therapy. The images on the left show widespread bone disease from the prostate cancer, including the skull. The images on the right show the dramatic response after completing four cycles of Lu 177 PSMA, with the normal excretion of the radiotracer seen in the liver, kidneys, and bladder.


Treatment puts the department, UFS, and hospital on the map

According to Dr Evbuomwan, the ability to administer this treatment puts the department, the UFS, and the hospital on the map, alongside other top universities within and outside the country. Says he: “It also creates an avenue for us to gather data for training, research purposes, and publications. We are now able to offer a promising, safe, and highly efficacious therapy for patients with MCRPC in the Free State. Some of these patients will no longer have to travel to other provinces to receive this treatment.”


“We are also well aware that not every patient will respond this way; however, proper patient selection is key in identifying responders – an area that is still being researched. We also do not know how long these patients will have their disease under control after the treatment. Nuclear medicine’s greatest cancer therapy success story is the treatment of well-differentiated thyroid cancer with radioactive iodine.” 

“After treatment, most of these patients remain cancer-free for a very long period of time, if not for life. With continuing research in the field of MCRPC radioligand therapy, we aim to improve the treatment modality, hopefully getting it to the success level of thyroid cancer therapy.”

 

News Archive

Message of appreciation from the UFS acting Vice-Chancellor and Rector: Prof Nicky Morgan
2017-01-04

Dear Colleagues, Students, Parents/Guardians, Alumni, and Friends of the university

The University of the Free State (UFS) successfully completed the 2016 academic year, with the official examination ending on 14 December 2016.  We have also completed the last of our graduation ceremonies, and are now preparing to accommodate the additional and ad hoc examinations in the coming weeks.
 
This comes after the university has successfully readjusted its academic programme in October 2016, subsequent to the disruption of activities and programmes for almost a month. All of this could not have happened without the extraordinary support and dedication of the staff and majority of the students at the UFS.
 
I would like to thank all our staff, parents/guardians, alumni, and friends of the UFS for the role they played during these challenging months in order to ensure that we could end the academic year successfully. If it was not for your understanding and uncompromising support, we would not have been able to complete the curricula, continue with the exams, and end the year in this way.
 
However, we all know that this was not an easy task. The sheer dedication and drive of our academic staff to adapt the mode of teaching and assessment of modules must be applauded, as it took courage and perseverance. Not only did they manage to complete the curricula, they also managed to do the assessment almost completely online. The incredible role of our administrative and support staff – including our security personnel – should also be acknowledged with deep appreciation.
 
This has been a learning experience for all, which has provided us with a solid base for academic recovery in the future.
 
During its quarterly meeting on 2 December 2016, the UFS Council expressed appreciation to all staff, students, and the university management for the successful completion of the 2016 academic year.
 
To all our alumni and donors who continued to support the UFS this year – thank you for your commitment, loyalty, and continued contribution.
 
Looking forward to 2017
The UFS announced on 7 December 2016 that it will be increasing tuition and housing and residence fees for 2017 by 8%. The approved increase in fees is in line with the recommendations by the Minister of Higher Education and Training, Dr Blade Nzimande, on 19 September 2016. The increases were approved by the UFS Council on 2 December 2016, with the understanding that it would be paid by the Department of Higher Education and Training by means of the fee adjustment grant for qualifying students with a combined family income of not more than R600 000 per annum.

The university management is aware of the economic realities in South Africa, as well as the financial pressure households are experiencing. The long-term financial sustainability of the UFS, as well as the financial constraints which impact teaching and learning, research, and community service, continues to remain of utmost importance to the Council and to the senior leadership of the UFS.
 
The university management stated its pro-poor approach to student funding on several occasions; that academically deserving students from poor and working class families should receive substantial financial support. For this reason – also because it does not place a burden on poor and working-class families – an increase in tuition fees aligned with the DHET proposal was submitted to Council for approval. The presidents of the Bloemfontein and Qwaqwa Campus Student Representative Councils were present and participated in the discussion on fees – also when Council approved the increase.
 
I am thankful to report that more applications for admission were received for 2017 (42 568) in comparison to 2016 (29 284), and we are excited to welcome first-year students to our campuses in January 2017. See 2017 calendar of events and information.
 
The necessary safety measures have been taken and contingency plans are in place when students return in 2017. The university management will continue to work with the South African Police Service to ensure stability on the campuses and the uninterrupted continuance of the Academic Project.
 
In conclusion, I would like to wish you a restful and safe Festive Season. Thank you once again for your crucial role in making the University of the Free State still one of the universities of choice in the country.
 
Best regards
 
Prof Nicky Morgan
Acting Vice-Chancellor and Rector
University of the Free State

 

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