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25 March 2022 | Story Anthony Mthembu | Photo Supplied
Bloemfontein Campus Choir
The Bloemfontein Campus Choir singing in front of the Main Building for students in celebration of Human Rights Day.

Students on the Bloemfontein Campus were treated to a lunch-hour music performance by the campus choir – an uplifting musical production led by the indomitable Sibongile Mngoma, conductor of the choir on the Bloemfontein Campus. The performance, which was in celebration of Human Rights Day, took place on 22 March 2022 in front of the Main Building.  “We realised that people were hungry to hear beautiful music and beautiful sounds, and we started these pop-up performances just to revive people’s spirit and to give them hope,” says Lucy Sehloho, Officer: Arts and Culture in the Department of Student Affairs. As such, the staff and students at the University of the Free State (UFS) can look forward to a series of pop-up performances by the UFS choirs, specifically on the Bloemfontein and South Campuses.

One institution, different sounds

According to Sehloho, “the choirs are all running on the same constitution and the same code of conduct”. However, they are slightly different in sound, and this is determined by the audience to whom the respective choirs cater, and the number of members involved in the choir. The Bloemfontein Campus choir is known to cover genres such as rap, trap, classical music, and South African choral music. However, the Qwaqwa Campus choir focuses on choral music and various African sounds, while the South Campus choir manoeuvres through most of the abovementioned genres.

Preparing for life as an artist after university 

It is important to note that the choirs are not just a safe space that encourages expression for young artists. Indeed, for many students it is also the beginning of a career. As such, they are taught lessons about financial literacy and the ability to brand themselves as artists. “One of the things I am teaching the students is how to price and cost themselves,” Sehloho highlighted. In fact, Sehloho argues that a major challenge among young performers when they leave university, is that – because they have never charged a fee for their service – they have no idea how to price and sustain themselves from the money they acquire. Consequently, industry experts are invited to provide insight into the realities of the world for artists once they start working. These industry experts include Dr Jerry Mofokeng wa Makhetha.

Future endeavours for the respective choirs

In addition to these lessons, the choirs have various projects that they are working on. The Bloemfontein Campus choir is currently planning performances for national holidays such as Freedom Day and Youth Day. The choir is also gearing up for a performance of Handel’s Messiah in celebration of Easter. The South Campus is specifically working towards the Network Festival in collaboration with Oranje Girls’ School. Furthermore, the Bloemfontein Campus choir will compete in the Sing for Gold competition in Barcelona this coming October. Once an institutional choir has been finalised, the Arts and Culture team will represent the UFS and the nation at the World Choir Games in 2023.

The main challenge experienced by the choirs

Although the choirs are succeeding in entertaining and uplifting the UFS community, there are still some challenges that hinder their growth to some extent. Racial diversity is one of these barriers. ‘’When someone looks at the choir, they don’t get to see the full picture of who we as the University of the Free State are in terms of diversity,’’ she explains. Therefore, Sehloho notes that the respective choirs are open to students from all walks of life in order to ensure racial and cultural diversity. As such, students who are interested in joining can contact Lucy Sehloho at  SehlohoLP@ufs.ac.za

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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