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UFS academics make a mark at the All Together Better Health Conference in Qatar

17 November 2023 | Story Reuben Maeko | Photo SUPPLIED

Prof Nyoni, Dr Omar Mohamed Al-Ansari and Dr James Campbell — Prof Nyoni hands over the Winterthur Doha Interprofessional Declaration to the President of Qatar University Dr Omar Mohamed Al-Ansari and the WHO Director for Health Workforce Dr James Campbell at the All Together Better Health Conference in Doha, Qatar.

A delegation of five academics from the University of the Free State (UFS) made significant contributions at the recently concluded All Together Better Health Conference (ATBH) in Doha, Qatar. Led by Prof Champion Nyoni, Senior Researcher in the UFS School of Nursing and current Chairperson of Interprofessional.Global, the team showcased their research to an international audience, further solidifying UFS’s commitment to advancing interprofessional education and collaborative practices.

Engagement at the Conference

The esteemed UFS academics, including Dr Lizemari Hugo-van Dyk (School of Nursing), Dr Anke van der Merwe (School of Health and Rehabilitation Sciences), Dr Riaan van Wyk (Clinical Skills and Simulation Unit), and Dr Benjamin Botha (Computer Science and Informatics), actively participated in the conference, presenting their research findings to over 600 delegates from around the world. The ATBH Conference brought together students, educators, researchers, and policymakers with a shared goal of advancing interprofessional education and collaborative practices.

UFS’s leading role in Interprofessional Education

Interprofessional education (IPE), the focal point of the conference, involves collaborative learning among students from multiple health and social care professions. The UFS has been a trailblazer in the IPE domain, boasting a robust IPE programme that has been running successfully for nearly a decade.

Leadership excellence by Prof Nyoni

Prof Nyoni, as the Chair of Interprofessional. Global, played a pivotal role in the conference, showcasing leadership and communication excellence on a global scale. Interprofessional. Global is a confederation of regional networks worldwide purposed to embed IPE as part of mainstream training for the health workforce globally. His welcome address during the grand opening ceremony, attended by esteemed dignitaries including Her Highness Sheika Moza bint Nasser, the President of Qatar University, and the Director for Health Workforce at the World Health Organization (WHO), marked a momentous occasion. Moreover, Prof Nyoni presented the Winterthur-Doha Interprofessional Declaration to Qatar University and the WHO, symbolically endorsing IPE as a strategy to enhance global health outcomes.

The Winter-Doha Interprofessional Declaration

Explaining the significance of the Winter-Doha Interprofessional Declaration, Prof Nyoni expressed his excitement, stating, “I am thrilled that the World Health Organisation was forthcoming to receive this declaration – symbolically endorsing IPE as a strategy to enhance our health outcomes.” He added that this declaration would influence global efforts towards true IPE integration, with global representatives within the IPE community contributing to this milestone.

Research presentations by UFS Academics

The UFS academics delivered impactful presentations at the conference. Drs Hugo-van Dyk and Botha, along with Prof Nyoni, discussed “An Online Programme for Clinical Facilitators in Health Professions Education: A missed opportunity for IPE.” Additionally, they presented on desktop-based virtual reality to enhance role clarification in interprofessional education. Drs Van der Merwe and Van Wyk, along with Prof Nyoni, presented “Educator needs regarding a simulation debriefing programme: A missed opportunity for interprofessional practice at a South African University.”

Global collaboration and appreciation

Dr Botha, a member of the African Interprofessional Education Network (AfrlPEN), expressed appreciation for the opportunity, stating, “We have made good milestones globally and we are committed to continue to impact and influence the global space.” Dr van der Merwe echoed this sentiment, acknowledging the chance to connect with like-minded professionals worldwide and expressing gratitude to the UFS for facilitating this opportunity.

Closing thoughts

The UFS delegation’s active participation at the ATBH Conference not only underscores the university's commitment to advancing interprofessional education but also reinforces its global leadership in this critical domain. The contributions made at this prestigious event exemplify the UFS’s dedication to collaborative practices that enhance healthcare outcomes on a global scale.

Dr Lizemari Hugo-van Dyk, Dr Anke van der Merwe, Dr Bennie Botha, Prof Champion Nyoni, Dr Riaan van Wyk- The UFS team at the All Together Better Health Conference in Doha, Qatar

Closing panel of the ATBH conference 2023

Her Highness Sheika Moza bint Nasser at the 11th ATBH conference

Dr Champion Nyoni delivers the keynote address.

News Archive

UFS study on cell development in top international science journal

2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
18 September 2008

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