Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
10 October 2024
iCAN Book Cover

The Centre for Teaching and Learning recently unveiled the fourth volume of the Initiative for African Narratives (iCAN), a vibrant celebration of diverse voices at the University of the Free State (UFS). This latest anthology features 48 stories presented in 10 of South Africa’s official languages: Afrikaans, English, isiNdebele, isiXhosa, isiZulu, Sesotho, Sepedi, siSwati, Tshivenda and Xitsonga. Contributors include Kovsie writers from all three UFS campuses, reflecting the university’s rich linguistic and cultural diversity.

“This initiative forms part of the university’s commitment to promoting multilingualism while providing a platform for a wide array of narratives,” said Dr Peet van Aardt, iCAN Coordinator. “Every student at the university has stories to tell – whether drawn from their personal experiences or shaped by their imagination.”

The launch, held on the Bloemfontein Campus, attracted around 150 students. Attendees were treated to musical performances by the Conlaures Choir, conducted by Omphemetse Phaswana, and a captivating saxophone solo by Thabo Dlamini from the Odeion School of Music. Representatives from the Academy for Multilingualism and African Languages Press were also present, underscoring the event’s focus on the intersection of language and expression.

This year's anthology, iCAN Vol. 4, is the ninth publication under the iCAN initiative in the past seven years. In addition to these collaborative anthologies, iCAN has also published several standalone works by solo student authors. Coordinated by senior student writer Siphila Dlamini, this volume showcases some of the finest writing talent across the UFS campuses.

Student of the year

Shortly after the iCAN launch, the Office of the Executive Dean of Student Affairs announced that Siphila Dlamini had been awarded the prestigious EDSA Student of the Year 2024 title. His contributions to student success and well-being were lauded as being aligned with the university’s strategic objectives.

Currently completing his Postgraduate Diploma in Governance and Political Transformation, Siphila plans to pursue a master’s degree next year. Reflecting on the award, he said, “This recognition, stemming from my work with iCAN, is a humbling reminder of the power of storytelling to transcend boundaries. It reaffirms my belief that by amplifying diverse voices and fostering creativity, we can spark change, inspire growth, and leave an indelible mark on our collective narrative.”

Siphila’s accolade marks the second consecutive win for an iCAN writer. Last year, the award was bestowed upon Tlotlisang David Mhlambiso from the Faculty of Education, further highlighting the initiative’s role in nurturing outstanding talent.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept