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16 September 2024 | Story André Damons | Photo Supplied
Dr Mampoi Jonas and Prof Jan Du Plessis
Dr Mampoi Jonas, senior lecturer in Paediatric Oncology and Prof Jan Du Plessis, Head of the Paediatric Oncology Unit at the University of the Free State (UFS).

A campaign like Childhood Cancer Awareness Month is vital in creating awareness and educating people about the early signs and symptoms of certain cancers. This can significantly improve the survival rate of young patients. More than 50% of people diagnosed with cancer live for more than five years, and some types of cancer have survival rates as high as 90%.

This is according to Prof Jan Du Plessis, Head of the Paediatric Oncology Unit, and Dr Mampoi Jonas, senior lecturer in Paediatric Oncology, at the University of the Free State (UFS).

“Early diagnosis is crucial because early-stage cancer is more responsive to treatment and less likely to be fatal. Due to the rarity of childhood cancer, many children get misdiagnosed or diagnosed too late with advanced stage disease. The delayed detection and diagnosis diminish the chances of successful treatment.

“Cancer awareness educates families, communities, primary-care nurses and doctors about the early signs and symptoms of certain cancers. When people are aware of these, they are more likely to be on the lookout for them when children present with suspicious clinical symptoms and signs. This also gives parents the confidence to seek help early and even make people better able to support those with the disease once a diagnosis is made,” say the paediatric oncologists.

Recorded incidences on the rise

Though childhood cancer is rare, representing only 1.2% of all cancers worldwide, the recorded incidences are increasing. In the US cancer is the number one cause of death among children, while more than 100 000 children worldwide die because of cancer.

Prof Du Plessis says there are more than 12 major types of childhood cancers and multiple subtypes. The most common types are leukaemia, lymphoma (tumours that begin in the lymph glands), brain tumours, nephroblastoma (cancer of the kidneys) and soft tissue sarcomas. Most cancers in children are thought to develop as a result of mutations in genes that lead to uncontrolled cell growth and eventually cancer.

According to Dr Jonas, most cancers in children are thought to develop because of mutations in genes that lead to uncontrolled cell growth and eventually cancer. Although environmental pollutants have been implicated in some cancers, our experience has been that most paediatric cancers rather occur sporadically.

The reasons for the increase of reported incidence of cancer in children, could be to the increase in population numbers and better awareness of childhood cancers. Another reason might be that more children are being diagnosed who were previously misdiagnosed, explains Prof Du Plessis.

Treatments

Childhood cancers are treated with chemotherapy, surgery and radiation therapy under the care of a paediatric oncologist. Not much can be done about the genetic mutations, but parents can ensure that their children stay safe in the sun (slip, slop, slap campaign – slip on a shirt, slop on some suncream and slap on a hat), get their children vaccinated against HPV infection, help their children stay active and keep a healthy weight and talk to them about smoking.

Prof Du Plessis says the South African paediatric oncology community are currently busy with a few research studies regarding standardising treatment protocols for certain childhood cancers. This is to find out how our children are responding to these protocols and to see if there are different factors affecting the outcomes of South African children. These protocols are based on international treatment protocols with a few adjustments for local circumstances and resources.

They are involved with the Hodgkins lymphoma, neuroblastoma, retinoblastoma, germ cell tumour studies and contributed to a research study evaluating the nutritional status and interventions to improve the nutritional status of local patients. Registrars presented local (Bloemfontein) data at an international conference (SIOP Africa) on hepatoblastomas and osteosarcomas.

“For many childhood cancer may not be a priority or something they would like to think about. Unfortunately for many of my patient’s parents the truth is that the day before their children were diagnosed with cancer, they were also not a cancer parent. However, their lives changed for ever with these four words: ‘Your child has cancer’.

“Childhood cancer is more than chemo and no hair. It is rather about resilience, strength, hope, family, courage, cuddles, and bravery. Your life will be changed for ever if you have ever seen a child fight cancer. Their smiles will make your heart melt and make you realise the importance of the simple things in life,” declare Prof Du Plessis and Dr Jonas.

Early warning signs for parents

The Childhood Cancer Foundation South Africa (CHOC) has a campaign which emphasises the importance of recognising the early warning signs of childhood cancer. They use Siluan’s Early Warning Signs to raise awareness and promote early diagnosis which are:

• S – Seek medical help early for ongoing symptoms
• I – White spot in the eye, new squint, sudden blindness or bulging eyeball.
• L – Lump on the stomach, pelvis, head, arms, legs, testicle, or glands
• U – Unexplained fever present for over two weeks, weight loss, fatigue, pale appearance, easy bruising, and bleeding
• A – Aching bones, joints, back, and easy fractures

• N – Neurological signs, a change in walk, balance or speech, regression, continuous headaches with/without vomiting, and an enlarged head

While these symptoms can be subtle or easily attributed to other causes, it’s important to consult a doctor if they persist or worsen. If you notice any of these symptoms in a child or teen, seek professional medical help promptly. Early detection of cancer saves lives in both children and teens.

News Archive

UFS outlines research achievements
2011-09-02

 

At the launch of the 2010 Annual Research Report, were from the left: Mr Robert Kriger, the director for Policy and Strategy at the National Research Foundation (NRF); Prof. Driekie Hay, Vice-Rector: Academic and Prof. Frans Swanepoel, Senior Director: Research Development.
Photo: Stephen Collett

The University of the Free State (UFS) is well on course for delivery on its most important academic duty as a research university. This was the message that came forward at the launch of the 2010 Annual Research Report of the UFS on 30 August 2011.

Speakers at the launch, which included Prof. Jonathan Jansen, Vice-Chancellor and Rector, as well as Prof. Driekie Hay, Vice-Rector: Academics outlined the key strategies and achievements of the UFS for the 2010 academic year. This included the establishment of a Postgraduate School at the UFS, the first of its kind at a public university in South Africa. Prof. Hay told guests that the aim of the Postgraduate School was to broaden research and deepens scholarship on postgraduate education in the country. She highlighted some initiatives the UFS undertook in 2010 to build and maintain its intellectual capital. Some of these initiatives included the appointment of seven senior professors and recruiting more female and black scholars and academics.   
Also speaking at the event was Mr Robert Kriger, the director for Policy and Strategy at the National Research Foundation (NRF). Kriger reflected on the brilliant minds of scholars such as Archie Mafeje, Lewis Nkosi and Dennis Brutus and argued for efforts to increase the country’s research output.
Some highlights of the 2010 Annual Research Report:
  • The total funding available for research at the UFS increased from approximately R199 million in 2009 to just over R210 million in 2010. A total of R31.8 million was made available from central university funds.
  • In 2010 the UFS was home to 92 NRF-rated researchers. During 2010, four researchers applied for re-evaluation and of these, two improved their rating, while a further five received a first-time rating.
  • The Faculty of Natural and Agricultural Sciences continue to be the most prolific producer of publications in accredited journals, while the Faculty of Education has shown a 54% increase in its publication output.
  • Staff members in the Physics department at the UFS Qwaqwa Campus published 22 papers in international peer-reviewed journals during 2010.
  • Also at the Qwaqwa Campus: Ms Khethiwe Mtshali,a postgraduate student in the parasitology research unit of the Department of Zoology and Entomology, received a best Honours presenter award at the 1st Annual Research symposium of the National Zoological Gardens of South Africa.

 

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