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16 September 2024 | Story André Damons | Photo Supplied
Dr Mampoi Jonas and Prof Jan Du Plessis
Dr Mampoi Jonas, senior lecturer in Paediatric Oncology and Prof Jan Du Plessis, Head of the Paediatric Oncology Unit at the University of the Free State (UFS).

A campaign like Childhood Cancer Awareness Month is vital in creating awareness and educating people about the early signs and symptoms of certain cancers. This can significantly improve the survival rate of young patients. More than 50% of people diagnosed with cancer live for more than five years, and some types of cancer have survival rates as high as 90%.

This is according to Prof Jan Du Plessis, Head of the Paediatric Oncology Unit, and Dr Mampoi Jonas, senior lecturer in Paediatric Oncology, at the University of the Free State (UFS).

“Early diagnosis is crucial because early-stage cancer is more responsive to treatment and less likely to be fatal. Due to the rarity of childhood cancer, many children get misdiagnosed or diagnosed too late with advanced stage disease. The delayed detection and diagnosis diminish the chances of successful treatment.

“Cancer awareness educates families, communities, primary-care nurses and doctors about the early signs and symptoms of certain cancers. When people are aware of these, they are more likely to be on the lookout for them when children present with suspicious clinical symptoms and signs. This also gives parents the confidence to seek help early and even make people better able to support those with the disease once a diagnosis is made,” say the paediatric oncologists.

Recorded incidences on the rise

Though childhood cancer is rare, representing only 1.2% of all cancers worldwide, the recorded incidences are increasing. In the US cancer is the number one cause of death among children, while more than 100 000 children worldwide die because of cancer.

Prof Du Plessis says there are more than 12 major types of childhood cancers and multiple subtypes. The most common types are leukaemia, lymphoma (tumours that begin in the lymph glands), brain tumours, nephroblastoma (cancer of the kidneys) and soft tissue sarcomas. Most cancers in children are thought to develop as a result of mutations in genes that lead to uncontrolled cell growth and eventually cancer.

According to Dr Jonas, most cancers in children are thought to develop because of mutations in genes that lead to uncontrolled cell growth and eventually cancer. Although environmental pollutants have been implicated in some cancers, our experience has been that most paediatric cancers rather occur sporadically.

The reasons for the increase of reported incidence of cancer in children, could be to the increase in population numbers and better awareness of childhood cancers. Another reason might be that more children are being diagnosed who were previously misdiagnosed, explains Prof Du Plessis.

Treatments

Childhood cancers are treated with chemotherapy, surgery and radiation therapy under the care of a paediatric oncologist. Not much can be done about the genetic mutations, but parents can ensure that their children stay safe in the sun (slip, slop, slap campaign – slip on a shirt, slop on some suncream and slap on a hat), get their children vaccinated against HPV infection, help their children stay active and keep a healthy weight and talk to them about smoking.

Prof Du Plessis says the South African paediatric oncology community are currently busy with a few research studies regarding standardising treatment protocols for certain childhood cancers. This is to find out how our children are responding to these protocols and to see if there are different factors affecting the outcomes of South African children. These protocols are based on international treatment protocols with a few adjustments for local circumstances and resources.

They are involved with the Hodgkins lymphoma, neuroblastoma, retinoblastoma, germ cell tumour studies and contributed to a research study evaluating the nutritional status and interventions to improve the nutritional status of local patients. Registrars presented local (Bloemfontein) data at an international conference (SIOP Africa) on hepatoblastomas and osteosarcomas.

“For many childhood cancer may not be a priority or something they would like to think about. Unfortunately for many of my patient’s parents the truth is that the day before their children were diagnosed with cancer, they were also not a cancer parent. However, their lives changed for ever with these four words: ‘Your child has cancer’.

“Childhood cancer is more than chemo and no hair. It is rather about resilience, strength, hope, family, courage, cuddles, and bravery. Your life will be changed for ever if you have ever seen a child fight cancer. Their smiles will make your heart melt and make you realise the importance of the simple things in life,” declare Prof Du Plessis and Dr Jonas.

Early warning signs for parents

The Childhood Cancer Foundation South Africa (CHOC) has a campaign which emphasises the importance of recognising the early warning signs of childhood cancer. They use Siluan’s Early Warning Signs to raise awareness and promote early diagnosis which are:

• S – Seek medical help early for ongoing symptoms
• I – White spot in the eye, new squint, sudden blindness or bulging eyeball.
• L – Lump on the stomach, pelvis, head, arms, legs, testicle, or glands
• U – Unexplained fever present for over two weeks, weight loss, fatigue, pale appearance, easy bruising, and bleeding
• A – Aching bones, joints, back, and easy fractures

• N – Neurological signs, a change in walk, balance or speech, regression, continuous headaches with/without vomiting, and an enlarged head

While these symptoms can be subtle or easily attributed to other causes, it’s important to consult a doctor if they persist or worsen. If you notice any of these symptoms in a child or teen, seek professional medical help promptly. Early detection of cancer saves lives in both children and teens.

News Archive

UFS outperforms SA higher education in EU-Saturn programme
2016-12-14

Description: Erasmus Mundus Tags: Erasmus Mundus 

Partnering between the UFS and other institutions
makes it possible for staff and students to study abroad.
Pictured from left front, are: Mareve Biljohn (EU-Saturn
at University of Groningen), Memory Mphaphuli (INSPIRE
at University of Ghent) and Wanda Verster (EU-Saturn at
Uppsala University). Back: Moliehi Mpeli (Erasmus Mundus
at University of Leuven).
Photo: Stephen Collett

The University of the Free State (UFS) strives to invest in its staff and students and a proven example can be seen in the latest cycle of the Erasmus Mundus EU-SATURN programme.

The UFS outperformed the higher education sector over the past five years as it had more exchange scholarships than most South African universities. A total of 16 (18%) out of the 89 local scholarships allocated until 2016 were from UFS. Stellenbosch University, with 14 scholarships, was second.

University one of main roleplayers
Chevon Jacobs, Senior Officer said: “Internationalisation at the UFS is a great achievement as the university allocated all available scholarships to eligible staff and students. She said the strong partnership history between the university and some European institutions, due to a similarity between the language and culture of especially Dutch-speaking countries, is one of the reasons for the success.

“We are very proud of our participation. We have invested for these predominantly young members to spend time abroad in furthering their qualifications,” she said.

The EU-Saturn project has been jointly co-ordinated for the past five years by the University of Groningen, Netherlands, and the UFS.

One of few projects funded by Erasmus Mundus
The Erasmus Mundus is an international partnership aimed at enhancing the quality of European higher education and the promotion of dialogue and understanding between people and cultures through co-operation with other countries. The EUROSA, EU-Saturn, Aesop and INSPIRE to name a few, are all programmes funded by the European Union through the Erasmus Mundus. These projects offer fully funded part-time or full-time postgraduate scholarships for study in Europe.

Some of the universities UFS students have studied at are the University of Groningen, the University of Newcastle, England, and the University of Ghent, Belgium.

Successful UFS grantees awarded scholarships over the past five years:
•    Maria Campbell (2014 – PhD) – University of Newcastle
•    Sethulego Matebesi (2014 – PhD) – Uppsala University
•    Lindie Koorts (2016 – PhD) – University of Groningen    
•    Reginald Makgoba (2013/2014 – Master’s) – University of Newcastle
•    Sanet Steyn (2013/2014 – Master’s) – University of Groningen  
•    Johnathan Adams (2015/2016 – Master’s) - Göttingen University
•    Eben Coetzee (2013/2014 - PhD) – University of Groningen
•    André Janse van Rensburg (2013/2014 – PhD) – University of Ghent
•    Martin Rossouw (2013-2015 – PhD) – University of Groningen
•    Jan Schlebusch (2013-2016 – PhD) – University of Groningen
•    Carel Cloete (2014-2016 – PhD) – University of Groningen
•    Nadine Lake (2014-2016 – PhD) – Uppsala University
•    Elbie Lombard (2014-2016 – PhD) – University of Ghent
•    Luyanda Noto (2014/2015 – PhD) – University of Ghent
•    Mareve Biljohn (2015/2016 – PhD) – University of Groningen
•    Wanda Verster (2015/2016 – PhD) – Uppsala University

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