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31 October 2025 | Story Martinette Brits | Photo Supplied
ASSAf
Prof Carlien Pohl-Albertyn (left) and Prof Serges Kamga from the University of the Free State have been elected to the Academy of Science of South Africa (ASSAf), recognising their excellence in research and academic leadership.

Two University of the Free State (UFS) academics have been elected to the Academy of Science of South Africa (ASSAf), joining the ranks of the nation’s most distinguished scholars. Prof Serges Kamga, Dean of the Faculty of Law, and Prof Carlien Pohl-Albertyn, NRF-SARChI Research Chair in Pathogenic Yeasts and Professor of Microbiology, were recently recognised for their outstanding contributions to research, scholarship, and the advancement of knowledge.

In addition, Dr Mutshidzi Mulondo, an academic in the Division of Public Health within the Faculty of Health Sciences who recently made history as the first academic from the UFS to be inaugurated to the prestigious Global Young Academy – a network institution of the United Nations Scientific Advisory Board – was selected to the South African Young Academy of Science (SAYAS) as one of the top young scholars recognised for engaged scholarship and scientific contribution. SAYAS provides early-career researchers with a platform to influence science, policy and innovation across South Africa and the continent.

Prof Vasu Reddy, Deputy Vice-Chancellor: Research, Innovation and Postgraduate Studies, who is also a member of the academy and a member of the ASSAf Council, says: “Membership in the Academy of Science of South Africa is a hallmark of scholarly distinction. It is to be entrusted with the stewardship of knowledge. More than this, it is an affirmation that one’s work resonates nationally and globally in advancing knowledge for societal good.”

 

Celebrating UFS excellence

Since its inauguration in 1996 by former President Nelson Mandela, ASSAf has championed the use of science for the benefit of society. Its mandate spans all fields of scientific enquiry, promoting scholarly excellence, evidence-based solutions to national challenges, and international collaboration. With these recent elections, 23 UFS staff members now hold membership of ASSAf, reflecting the university’s growing national and global research impact.

SAYAS, established under ASSAf, empowers young scientists to shape scientific dialogue, influence policy, and tackle pressing societal challenges. Its mission is to create a vibrant community of early-career researchers driving innovation, education, and sustainable development.

Prof Reddy also remarks: “ASSAf and SAYAS are platforms where excellence meets responsibility, purpose, and service. It is, in fact, a call to shape the scientific imagination of the nation, to mentor with purpose, and to lead with intellectual generosity. My heartfelt congratulations to our colleagues who have received recognition from the academy. You make the UFS proud.”

 

Prof Serges Kamga: Human rights and inclusive development

For Prof Serges Kamga, being elected to ASSAf is both an honour and a validation of his lifelong commitment to the advancement of human rights and social justice. “My election demonstrates that I am on the right track in terms of scientific knowledge and activity to remove barriers between people and obstacles to full development of their intellectual capacity,” he says.

His research focuses on the human right to development, socio-economic inclusion, and equality, particularly for vulnerable groups such as persons with disabilities. “I rely on scientific evidence to stress the need to build an equalitarian world, a world without barriers to the full development of human potential,” he explains. Personal experience in witnessing poverty and underdevelopment across Africa inspired him to ask: “If development is a human right inherent to all, why are we poor in Africa? Who pulls the strings of poverty nationally and globally, and why?”

Prof Kamga intends to use his ASSAf membership to strengthen interdisciplinary collaboration and foster responsible societal futures. “My engagement with colleagues will seek ways to break down artificial barriers between disciplines, institutions, and sectors to foster groundbreaking discoveries at the intersection of fields. Modern lawyers should bridge the gap between theory and practice to ensure relevance to their environments.” He also hopes to guide the next generation of legal scholars to combine strong theoretical foundations with practical relevance: “They should connect across disciplines, generate new knowledge, and advance innovative, sustainable solutions to society’s contemporary and future challenges.”

 

Prof Carlien Pohl-Albertyn: Exploring the frontiers of fungal biology

Prof Carlien Pohl-Albertyn describes her election as “a meaningful recognition of my contributions to the national research landscape”. Her research investigates bioactive lipids in pathogenic fungi, focusing on molecules such as oxylipins and prostaglandins that influence fungal virulence and host-pathogen interactions. “By exploring these pathways, I hope to uncover novel targets for antifungal therapies, especially in the context of rising antifungal resistance,” she says. Her work has already shown how polyunsaturated and marine-derived fatty acids can inhibit biofilm formation, a key virulence factor, in Candida species.

Her research also has public health significance through the South African Fryer Oil Initiative (SAFOI), which monitors the quality of frying oils nationwide. “My research on fungal lipids and edible oils is connected by a central theme: understanding how lipids influence health, whether through microbial pathogenicity or human nutrition,” she explains.

Mentorship is equally central to her work. “I foster collaboration and encourage open exchange of ideas, with shared credit and authorship as a non-negotiable principle. Students are supported to publish in reputable journals and present at both local and international conferences, and I actively connect them with global collaborators to help them see themselves as equals on the international stage. Over the years, I have had the privilege of mentoring a diverse group of students and postdocs (many of them first-generation scholars) who have gone on to lead in academia, industry, and government. Our current group reflects a rich diversity of cultures, languages, and identities, and I am committed to continuing the tradition of care and excellence that was instilled in me by my own mentors.”

Prof Pohl-Albertyn is optimistic about future discoveries in her field. “Advances in lipidomics and systems biology are allowing us to study bioactive lipids with increasing precision. Understanding how fungi adapt their lipid pathways in response to environmental pressures, such as climate change or antimicrobial exposure, could reveal new strategies to combat fungal infections and predict emerging pathogens.” She also hopes to use her ASSAf platform to advocate for greater awareness and investment in fungal disease research and to promote equitable access to research funding for African scientists.

 

Dr Mutshidzi Mulondo: Public mental health in a digital age

Dr Mutshidzi Mulondo’s research focuses on mental health, particularly the implementation of digital strategies for public mental health. Mental health, a silent pandemic of our generation, continues to receive limited attention. “My current research looks at digital public mental health strategies, allowing for holistic care and support, particularly in lower- and middle-income countries.” This research is an effort to advance public health strategies that prioritise mental health and health equity.

Dr Mulondo sees the academy as a platform to influence national scientific dialogue and shape policy through emerging efforts such as science diplomacy. “This opportunity allows me to impact policies, specifically in public health, for the betterment of people’s lives. Young scientists need more opportunities to interact with established scientists for intergenerational collaboration. This platform provides young scientists with mentorship as future national and global leaders. Furthermore, the platform provides young scientists with access to other leading scholars for interdisciplinary collaboration to address some of the wicked challenges of our generation.” 

Through SAYAS, Dr Mulondo hopes to contribute to programmes that support the growth of young scientists, increase public understanding of science, and foster sustainable development. “I look forward to participating in these efforts to better place our nation and continent.”

 

A growing legacy of scholarship

The election of Prof Kamga, Prof Pohl-Albertyn, and Dr Mulondo underscores the UFS’ commitment to nurturing excellence across disciplines – from law and the humanities to microbiology and public health. Through the work of ASSAf and SAYAS members, the UFS continues to shape the scientific and academic landscape of South Africa, supporting a vibrant, inclusive, and forward-looking research community. Prof Reddy also emphasises that “recognition by a national academy is a powerful endorsement of one’s scholarly journey. It signals that your voice matters in shaping the intellectual, innovation, and developmental landscape as we aspire to create responsible societal futures”.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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