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Prof Botma Visser takes on rust diseases threatening South Africa’s wheat

09 September 2025 | Story Martinette Brits | Photo Stephen Collett

Safeguarding one of the world’s most vital staple foods was at the heart of the inaugural lecture delivered by Prof Botma Visser, Professor in the Department of Plant Sciences at the University of the Free State (UFS), on Wednesday 3 September 2025. Prof Visser shared insights from nearly two decades of research into wheat rust – a devastating crop disease that threatens both South Africa’s harvests and global food security.

“Wheat production in South Africa is threatened by three fungal pathogens that cause rust disease on the crop. Understanding the factors that contribute to virulence on locally grown cultivars is crucial to ensure continued wheat production,” said Prof Visser.

The fight against evolving wheat rusts

For the past 17 years, Prof Visser’s research has focused on the genetic structure of rust populations and the risks they pose to food security. His work has shown that these populations are dynamic and constantly changing due to genetic mutations within existing races, as well as the introduction of new races into South Africa.

“Computer modelling showed that rust can spread over vast distances by prevailing winds. During the 20th Century, at least four Southern African stem rust races managed to move across the Indian Ocean from Southern Africa to Australia. South Africa, in turn, received multiple new races from mid-Africa across Zambia and Zimbabwe, without any means of stopping these introductions,” he explained.

To respond to this challenge, his team recently implemented MARPLE (Mobile And Real-time Plant disEase) diagnostics using fourth-generation nanopore sequencing technology. This approach allows the rapid characterisation of fungal isolates, specifically targeting genes linked to fungicide resistance and virulence.

“This work,” Prof Visser noted, “is part of an effort to safeguard global wheat production.”

His research is a collaborative effort with Prof Willem Boshoff (Department of Plant Sciences, UFS) and Dr Tarekegn Terefe (Agricultural Research Council – Small Grain, Bethlehem). Together, their work has positioned the UFS as an internationally recognised centre of excellence in wheat rust research.

About Prof Botma Visser

Prof Botma Visser obtained his BSc in Botany and Microbiology (1988), BSc Honours in Microbiology (1989), and MSc in Botany (1993) at the University of the Free State, where he also completed his PhD in Botany in 2004.

His career spans more than 18 years of research into wheat rust pathogens, combining annual surveys, race pathotyping, molecular genetics, and cutting-edge sequencing technologies. His expertise has not only advanced understanding of rust population dynamics in South Africa but also contributed to global collaborative studies on crop disease.

News Archive

UFS Council unanimously reappoints Dr Khotso Mokhele as Chancellor

2015-04-02

Dr Khotso Mokhele, Chancellor of the University of the Free State

The Council of the University of the Free State (UFS) unanimously reappointed Dr Khotso Mokhele as Chancellor during its quarterly meeting held on 13 March 2015. He was first appointed in this portfolio by the Council on 4 June 2010.

“It is an honour for the Council to reappoint someone of this stature as Chancellor of the UFS. With his solid academic background and high profile in the business world, Dr Mokhele has been a great asset to the UFS. On behalf of the Council and the university community, I extend a word of appreciation for the work he has done during his first term as Chancellor of the UFS. He is an exceptional leader, and the university community is looking forward to have him as Chancellor for a second term,” said Judge Ian van der Merwe, Chairperson of the UFS Council.

Dr Mokhele was awarded a BSc Agriculture from Fort Hare University, and continued his studies at the University of California Davis (USA) on the Fulbright-Hays Scholarship Programme, completing his MSc (Food Science) and PhD (Microbiology). He was subsequently a postdoctoral fellow at Johns Hopkins University School of Medicine (USA) and the University of Pennsylvania School of Medicine (USA). Dr Mokhele is the recipient of honorary doctorates from nine South African universities including the UFS, and from Rutgers University in the USA.

He was Chairman of the Rhodes Scholarship Selection Committee for Botswana, Malawi, Namibia, Lesotho and Swaziland (2007-2011), and served on the South Africa at Large Rhodes Scholarship Selection Committee for more than 10 years. As President and Chief Executive Officer (CEO) of the Foundation for Research Development (1996-1999) and the NRF from 1999 to 2006, Dr Mokhele played a central role in providing visionary and strategic direction to the South African science system. He was the Founder President of the Academy of Science of South Africa (ASSAf), Founder President and CEO of the National Research Foundation (NRF), Chairperson of the Economic Advisory Council to the Premier of the Free State (2001-2004), and a member of the Advisory Council on Innovation to the Minister of Science and Technology (2003-2007). His role in securing government and international support for the Southern African Large Telescope Project (SALT) is evidence of his dedication to science in South Africa. The success of this project laid the basis for South Africa being selected to host more than 70% of the Square Kilometre Array, an international mega telescope for radio astronomy.

In recognition of his contribution to the development of science, he was the recipient of the Technology Top 100 Lifetime Achievers Award in 2009 and the National Science and Technology Forum Award in 2005. His role in science is recognised internationally. He was an elected Vice-President: Scientific Planning and Review of the International Council for Science and Chairperson of its Committee for Scientific Planning and Review (2005-2008) as well as a member of the Committee on Developing and Transition Economy Countries of the International Social Science Council (2008-2010). He also represented South Africa on the executive board of UNESCO, and was awarded the Member Legion of Honour of the Republic of France for his work in strengthening scientific ties between South Africa and France.

Dr Mokhele currently serves as Special Advisor to the Minister of Science and Technology, the Honourable Naledi Pandor. His current corporate positions include: Non-Executive Chairman: Board of Directors, Impala Platinum Holdings Ltd (Implats); Lead Independent Non-Executive Director: African Oxygen Ltd (Afrox); Non-Executive Director of Zimbabwe Platinum Holdings Ltd (Zimplats); Hans Merensky Holdings Ltd; and Tiger Brands Ltd. He is the President of the Hans Merensky Foundation (South Africa) and a Trustee of SciDev.Net (a web-based scientific magazine based in London, UK) and Start International Inc (USA).

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