Latest News Archive

Please select Category, Year, and then Month to display items
Years
2019 2020 2021
Previous Archive
18 June 2019 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Dr Christine Engelbrecht from the Agricultural Research Council
Dr Christine Engelbrecht from the Agricultural Research Council presented the keynote lecture on climate dynamics, predicting that El Niños will double in frequency towards the end of the century.

The world will need nearly double the current food supply by 2050 to feed an ever-increasing world population. This is a mammoth, almost impossible task.

Building on knowledge

According to UFS Rector and Vice-Chancellor, Prof Francis Petersen, if we approach challenges such as these with scientific level-headedness, systematically build on knowledge and experience gained, and draw on similar inputs from other specialist fields, the seemingly impossible becomes possible.

“To what extent do we integrate our knowledge across sectors – within the university and outside the university; on the continent as well as globally?” he asked the 300-plus delegates, which included animal scientists, students, and various other role players in the livestock sector, at the 51st South African Society of Animal Science (SASAS) congress on the Bloemfontein Campus of the University of the Free State (UFS). 

Willingness to adapt to new strategies


The theme of this year’s congress was: Managing the ecological footprint of livestock through efficient production. The congress provided a platform for discussions on the impact of livestock production – bringing in elements of critical thinking, as well as the willingness to adopt new strategies. 

During the congress, workshops on topics such as silage, predation management, intensive sheep production, prickly-pear utilisation, and animal welfare provided delegates with the opportunity to discuss challenges faced by the South African livestock producer.

Dr Christine Engelbrecht (Meteorology) from the Agricultural Research Council presented the first keynote address, focusing on climate dynamics. 

“We have high-impact weather systems across Southern Africa. It is projected that strong El Niños are to double in frequency towards the end of the 21st century,” said Dr Engelbrecht. 

She further predicted temperature increases of between 4 and 7 degrees Celsius in the interior before the end of the century. Over the Free State, Northern Cape, and North-West Province, we can expect shorter frost seasons, significant increases in maximum temperatures for both summer and winter, as well as more frequent El Niño-induced droughts. 

Ecological footprint of food

Improved production outputs need to be achieved by using less land, water, and available energy, while ensuring that the degradation and pollution of natural resources are limited. A scientific approach would be a viable option to improve the efficiency of livestock production.

SASAS President, Prof Este van Marle-Köster from the University of Pretoria, pointed out that all food had an ecological impact.

Dr Frikkie Maré, Head of the Department of Agricultural Economics at the UFS, presented a keynote lecture on managing the footprint of beef through efficient production. Comparing the water footprint of different cattle breeds, his question was what could be done to reduce this. 

Animal welfare was introduced to the congress for the first time. Prof Cathy Dwyer from Scotland’s Rural College presented a session on, ‘Can animal welfare contribute to improved production efficiency?’

The oldest conception of animal welfare is the five freedoms adapted to the five welfare needs of animals, namely a suitable environment, a suitable diet, exhibiting normal behaviour patterns, being with or being apart from other animals, and protection from pain, injury, suffering, and disease. Studies demonstrate that animal welfare can be an important and effective part of production efficiency, and that animal welfare should be seen as an integral component of improving the sustainability of livestock. 

Prof HO de Waal from the Predation Management Centre at the UFS presented a session on the impact of predation on livestock production, with the tile: The need for coordinated predation management in South Africa – quo vadis? He said: “The current approach to predation management is fragmented and uncoordinated. Solutions for the management of human-wildlife conflict require a South African institutional memory. Most of the information on predation and the hunting of predators is held by specialist predator hunters and farmers. In a system of coordinated predation management, farmers and government are equal partners, each with specific responsibilities.”

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept