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14 May 2019 | Story Thabo Kessah | Photo Tsepo Moeketsi
Prof Ashafa
Prof Ashafa’s research documents plants used by the Basotho in the management of different ailments.

The Phytomedicine and Phytopharmacology Research Programme (PPRP) in the Department of Plant Sciences on the Qwaqwa Campus researches the biological effects of medicinal plants used in the folkloric medicine of the Eastern Free State, particularly to explore the values and contribution of indigenous knowledge systems (IKS) towards broader scientific research. This is according to the programme’s principal investigator and researcher, NRF C2-rated researcher, Professor Anofi Ashafa. 

 “Our research is mainly aimed at documenting plants used by the Basotho in the management of different ailments and to further discover, isolate, and purify active phytoconstituents that are responsible for disease curation or amelioration, thereby assisting in the global promotion of accessible and affordable medication in developing countries,” said Prof Ashafa. 

Since 2012, the PPRP has worked extensively on Basotho medicinal plants (BMP) used as antimicrobials, antioxidants, antidiabetics, antitubercular, anticancer, anthelmintic, and antidiarrheal agents, starting from biological activities up to the  evaluation of the toxicity of these plants for the kidney, liver, and heart functions in order to establish safe dosage parameters. These activities have led to the discovery of four potent antidiabetic biomolecules that are awaiting the processes of patency and commercialisation. Additional outputs include 104 published peer-reviewed articles , 7 postdoctoral fellows, 6 PhDs, 9 master’s, and 16 honours graduates. 

“Our research informs teaching and the development of expertise in ethnobotany, 
phytomedicine, and phytopharmacology in order to contribute to the National Development Plan (NDP) through human capacity development, skills, and knowledge transfer.

The group is also investigating some medicinal plants on the endangered red list of the South African National Biodiversity Institute (SANBI), through micropropagation and field trials as well as proposing conservation strategies to preserve these valuable species.

The PPRP consists of postdoctoral fellows, PhD, master’s, and honours students and research is done in collaboration with several local and international universities as well as the Agricultural Research Council of South Africa. 


News Archive

Plant-strengthening agent a result of joint effort between UFS and German company
2015-07-27

Research over the past few years has showed that the agent applied mostly as a foliar spray subsequently leads to better seedlings as well as growth and yield enhancement of various crops.

The application of a plant-strengthening agent in the agricultural industry has, until recently, been largely ignored, says Dr Elmarie van der Watt of the Department of Soil, Crop, and Climate Sciences at the University of the Free State (UFS). The agent was co-developed by researchers at the UFS and a German company.

The product is moving into new markets, such as China, Vietnam, the USA, and Australia.

ComCat® was the result of extensive research by the German company Agraforum AG. Commercialisation was limited initially to Europe, while research was expanded to other parts of the world, with the University of the Free State as the main research centre.  ComCat® is a unique, non-toxic plant strengthening agent derived from wild plants. It enhances plant growth and yield, as well as resistance against abiotic and biotic stress factors.

Dr Van der Watt says that, in nature, plants communicate and interact by means of allelochemicals (the inherent silent tool of self-protection among plants) and other phytochemicals (chemical compounds that occur naturally in plants), as part of their resistance mechanisms towards biotic and abiotic stress conditions.

Most wild-plant varieties are usually well-adapted to resist these stress factors. However, monoculture crops have lost this ability to a large extent. “Active compounds contained in extracts from wild plants applied to monoculture crops can potentially supply the signal for the latter to activate their dormant resistance mechanisms.” 

Research over the past few years has showed that the agent applied mostly as a foliar spray subsequently leads to better seedlings as well as growth and yield enhancement of various crops.  A major advantage is that, despite its enhancing effects on root development and yield, it does not induce unwanted early vegetative growth that could jeopardise the final yield, as happened in the past for nitrogen application at an early growth stage. 

Dr Van der Watt says, “Physiological data on the effect of the natural bio-stimulant product on photosynthesis, respiration, and resistance towards biotic stress conditions indicate that it can be regarded as a useful tool to manipulate agricultural crops. Research also showed that the field of application for this natural product is never-ending, and new applications are being investigated every day.”

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