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Global genealogy explored at UFS guest lecture
Karen Ehlers, lecturer in Department of Genetics; Prof Eugenia D’Amato, guest lecturer and Associate Professor: Department of Biotechnology at the UWC, and Prof Paul Grobler Head of Department: Genetics at the UFS.

Prof Eugenia D’Amato held a lecture at the University of the Free State (UFS) Department of Genetics about the research activities she has conducted in her unit at the University of the Western Cape (UWC), in the Forensic DNA lab of the Faculty of Natural Sciences.
 
The lecture focused on research topics she has piloted, including the use of forensic markers in South Africa. Prof D’Amato also spoke on food forensics, the identification of anti-apartheid activists, understanding human genetic variation, and the implementation of novel/refined methods, with a strong emphasis on the forensic use of Y chromosome-based information.

She concluded her PhD studies at the University of Buenos Aires in Argentina, at the forensic lab. Currently, Prof D’Amato participates in numerous genotyping international forensic collaborations.

 “A survey of existing genetic diversity,
the distribution of diversity, the forensic
parameters and applications are a few of
the subject matters which are important
components of the GlobalFiler project.”
Prof Eugenia D’Amato

She also belongs to the working committee of the “Innocence Project South Africa”.

Her training and subsequent experience in population genetics facilitated the design of a Y chromosome “kit”, as well as the analysis and successful identification of various individuals from highly degraded DNA. Her lecture revealed interesting statistics about how poorly represented African diversity is in the existing world population databases. She explained that mechanisms that drive differentiation include random “genetic drift” and historic demographic processes.
 
Prof D’Amato indicated that her “Database Projection” project for 2018/2019 aims at profiling the population groups of South Africa, Lesotho, and Zimbabwe. She further explained that a powerful tool for forensic application has been developed, and that there is potential for other applications including haplogroup prediction and the study of demographic history, that will aid her projects in the future.

News Archive

Rare tumour removed in groundbreaking surgery
2011-08-06

 

Mr Carel Botes and Prof. Francis Smit with a model of the human heart
Photo: Earl Coetzee

A team of surgeons, headed by Prof Francis Smit, Head of our Department of Cardiothoracic Surgery at our Faculty of Health Sciences, performed open heart surgery on a male patient with a malignant tumour.

What makes this operation unique, is that the suspicious mass that was identified in the heart was a rapidly growing and a highly invasive cardiac tumour, which has only been seen in a small number of patients worldwide.

Without the necessary surgery or heart transplant, the prognosis of the patient would have been zero.

The patient, Mr Carl Botes, a 51-year-old farmer from Hoopstad, opted for the tumour to be removed rather than having a heart transplant.  Although both options would involve major risks and challenges, the transplant was the least feasible due to logistics, the waiting list for recipients and the lack of donors.

In the, highly complex, 10-hour operation, performed in the Universitas Academic Hospital in Bloemfontein, the entire right heart chamber had to be removed and the heart reconstructed.

After prolonged hospitalisation of five weeks, Mr Botes was discharged.

Currently he is fully functional and continuing with his active lifestyle.  After three months, all investigations and scans indicate that he is doing very well and has no complaints of fatigue, shortness of breath and palpitations – symptoms which occurred before the removal of the tumour.

For further information contact:
Prof Francis Smit
051-4053861
smitfe@ufs.ac.za
 

Media Release
6 August 2011
Issued by: Lacea Loader
Director: Strategic Communication
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: news@ufs.ac.za

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