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26 April 2018 Photo Supplied
Pretzel-formed fossil of great evolutionary interest
Slab with holotype of Parapsammichnites pretzelifornic from the Urusis Formation, Namibia. Scale bar is 1cm.Picture was taken from Buatois et al., 2018.

The acclaimed scientific journal, Nature, recently published an article about a trace fossil in approximately 543-million-year-old rocks, which elucidates the evolution of the first animals that appeared on Earth and lived in the sea.  

Affiliated Professor in the Department of Geology at the University of the Free State (UFS) Prof Gerard Germs formed part of a team that conducted research with the aim of understanding how the evolution of the first multicellular animals came about and how the Cambrian explosion took place. Prof Germs is of great value to the team for his extended field geological knowledge.

An article which he co-authored was published in the Nature Scientific Reports. The title of the article is: “Sediment disturbance by Ediacaran bulldozers and the roots of the Cambrian explosion”. The international group of writers included authors from Canada, Spain and South Africa. 

Occurrence of the Cambrian explosion
Prof Germs explains the Cambrian explosion: “During the long (4.5-billion-year) history of the Earth, the first life originated and subsequently evolution of plants and animals took place from one-cellular organisms to multicellular vertebrate animals and seed plants. Approximately 573 million years ago the first multicellular animals appeared on the scene. Sometime afterwards, approximately 540 million years ago, a kind of explosion in the origin of many new animal species occurred. This explosion is known as the Cambrian explosion.”

The team studied Earth sediments which are somewhat older than the Cambrian explosion. Such sediments are approximately 573 to 541 million years old and form part of the Ediacaran (late Neoproterozoic) period.

“My discoveries of the past, of among others, the oldest animal with a carbonate skeleton (Cloudina) and of complex horizontal Cambrian-type “worm” tracks (treptichnids) in Ediacaran sediments of Namibia have demonstrated that the Cambrian explosion occurred more gradually than previously thought. This has recently been confirmed in the article that was published in the Nature Scientific Reports.”

Pretzeliformis bulldoze to search for food
According to the article there is evidence that   during the Ediacaran period   worm-like animals such as the Parasammichnites pretzeliformis were already so far developed that they, due to coelom development and size increase, for the first time in the history of the Earth, were able to disturb and bulldoze sediments.  In this way they were able to find a new food source in sea sediments. Bulldozing animals were previously thought to have originated only during and after the Cambrian explosion and not during the older Ediacaran.

“Another major aim of my cooperative research is to improve our knowledge of the geology of the Ediacaran to early Cambrian of South Africa and Namibia. We also intend to establish how the assembly of the supercontinent Gondwana took place. This improved knowledge can be of great future economic interest since large oil, gas and limestone sources occur in Ediacaran-age sediments outside South Africa”.

News Archive

Science is diversifying the uses of traditional medicines
2017-07-17

Description: Dr Motlalepula Matsabisa  Tags: traditional medicines, Indigenous Knowledge Systems, Dr Motlalepula Matsabisa, Malaria, priority disease  

Dr Motlalepula Matsabisa.
Photo: Anja Aucamp

According to the World Health Organisation, a large majority of the African population are making use of traditional medicines for health, socio-cultural, and economic purposes. In Africa, up to 80% of the population uses traditional medicines for primary healthcare.

The Indigenous Knowledge Systems (IKS) was identified as a lead programme under the directorship of Dr Motlalepula Matsabisa. Research undertaken by the IKS Lead Programme focuses on some key priority diseases of the country and region – including malaria, HIV, cancer, and diabetes.
 
Not just a plant or tree

Malaria is a priority disease and is prevalent in rural and poor areas, resulting in many traditional health practitioners claiming to treat and cure the disease. There may well be substance to these claims, since as much as 30% of the most effective current prescription medicines are derived from plants.  For instance, chloroquine, artemisinin for malaria, Metformin for diabetes, Vincristine and Vinblastine for cancer, are plant-derived drugs.  

Dr Matsabisa’s current research is investigating a South African medicinal plant that has been shown to have in vitro antiplasmodial activity, with subsequent isolation and characterisation of novel non-symmetrical sesquiterpene lactone compounds offering antimalarial activity. These novel compounds are now patented in South Africa and worldwide. This research is part of the UFS and South Africa’s strive to contribute to the regional and continental malaria problem. The UFS are thus far the only university that has been granted a permit by the Medicines Control Council to undertake research on cannabis and its potential health benefits.

“All of these projects are aimed
at adding value through the scientific
research of medicinal plants, which
can be used for treating illnesses,
diseases, and ailments.”

Recognition well deservedThrough Dr Matsabisa’s research input and contributions to the development of the pharmacology of traditional medicines, he recently became the first recipient of the International Prof Tuhinadrin Sen Award from the International Society of Ethnopharmacology (ISE) and the Society of Ethnopharmacology in India. ISE recognises outstanding contributions by researchers, scientists, and technologists in the area of medicinal plant research and ethnopharmacology internationally.

More recently, Dr Matsabisa undertook research projects funded by the National Research Foundation, as well as the Department of Science and Technology, on cancer, gangrene, and diabetes. He is also involved in a community project to develop indigenous teas with the community. He says, “All of these projects are aimed at adding value through the scientific research of medicinal plants, which can be used for treating illnesses, diseases, and ailments”.

Dr Matsabisa has worked with many local and international scientists on a number of research endeavours. He is grateful to his colleagues from the Department of Pharmacology in the Faculty of Health Sciences, who are dedicated to science research and the research of traditional medicines. The IKS unit also received immense support from the Directorate of Research Development.

 

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