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25 April 2018 Photo Oteng Mpete
UFS and Medtronic collaboration set to enhance cardiac
From the left: Zampieri Luigi: Medtronic; Dania Choucair: Medtronic; Peter Fuller: Medtronic; Prof Francis Petersen: UFS Rector and Vice-Chancellor; Prof Gert van Zyl:Dean of the Faculty of Health Sciences, and Eline Visser: Medtronic.

A new Cardiac Simulation laboratory will be opened and hosted within the School of Biomedical Sciences’ Clinical Simulation and Skills Unit, at the University of the Free State’s Bloemfontein Campus. The new laboratory is a result of a partnership between Medtronic and UFS. 

The new laboratory will be used to enhance training for cardiothoracic, cardiology, vascular surgery, anaesthesiology and multiprofessional teams   such as doctors, nurses and allied health professionals. The establishment of the laboratory will be made possible by the generous provision of equipment for the establishment and operation of the Cardiac Simulation laboratory by Medtronic.  

Prioritising of patients at the heart of collaboration 

The development of a Cardiac Simulation laboratory at the UFS will not only benefit the training of specialists in various fields of specialisation but will also improve patient safety and reduce complication and mortality rates. The UFS is proud to be part of this initiative to train healthcare professionals to the benefit of the patients.

The Medtronic and UFS contract signing was attended by key stakeholders who included Prof Francis Smit: Head of Cardiothoracic Surgery; Prof Mathys Labuschagne: Head of the Clinical Simulation and Skills Unit; Prof Gert van Zyl: UFS Dean of the Faculty of Health Sciences and Prof Francis Petersen: UFS Rector and Vice-Chancellor. In attendance from Medtronic were Dania Choucair: Medtronic Director Clinical Research and Medical Education; Peter Fuller: Medtronic Country Director; Zampieri Luigi: Business Director   Cardiovascular Group; and Eline Visser: Business Manager   Structural Heart.

The Cardiac Simulation laboratory will make use of part task trainers, medium- and high- fidelity simulation as well as virtual-reality simulation to develop integrated interdisciplinary simulation programmes. These programmes are essential for proficiency development through deliberate practice and should become a statutory requirement for future trainees.

Objective and improved quality of training  

Standard cardiothoracic surgical training programmes are still based on the apprentice model. It implies that registrars in all programmes will attain surgical competency in addition to theoretical training fulfilling minimum statutory requirements for licensing and independent practice. It is highly dependent on surgical volumes, attitude of trainers and perceived surgical ability of the trainee. At best, it produces a mixed bag of competency levels. 

Well-designed integrated interdisciplinary simulation programmes offer an alternative that allows for deliberate practice in an organised step-wise progression model, with inbuilt assessment and feedback systems. This allows for proficiency training rather than competency training in which clear objectives can be met.

The UFS cardiothoracic programme is being designed as a hub and spoke model for South Africa and sub-Saharan Africa, combining distance learning with an onsite high-fidelity simulation and assessment centre. Off-site training in crew resource management or CRM (which addresses communication, decision-making, team-building and maintenance, workload management and situational awareness management), educational theory, surgical theory and basic bench model simulation will be provided. 

Multidisciplinary streams of knowledge 
According to Profs Francis Smit and Mathys Labuschagne, the role of simulation is a dynamic process of continuous movement between theory, simulation and clinical exposure.  “We strive to create an environment where there is free flow between these different components. Registrars and students come from different educational and cultural backgrounds in South Africa and Sub-Saharan Africa and by allowing deliberate practice for students with different needs to practice in their own time is contributing tremendously to students’ individual outcomes and development in the specialty.” 

This dynamic fulfils the needs of students with different competency levels and previous clinical exposure. Debriefing and formative assessment per session are pre-requisites for attending high-fidelity and virtual-reality simulation sessions at the Cardiac Simulation laboratory, because this kind of feedback contributes to the clinical and surgical development as well as inter-professional collaboration of the trainees. 

News Archive

Nanotechnology breakthrough at UFS
2010-08-19

 Ph.D students, Chantel Swart and Ntsoaki Leeuw


Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil. 

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)  

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

 

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.  

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
18 August 2010
 

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