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13 August 2018 Photo Charl Devenish
Mountain research Maloti-Drakensberg
Tucked in the foothills of the Maloti-Drakensberg Mountains is the Qwaqwa Campus of the University of the Free State (UFS), the home of the Afromontane Research Unit (ARU).

Mountains and highlands have always played an important role in the history of mankind. They produce economically essential goods and services (such as fresh water), host unique biodiversity, and offer unique recreational and tourism opportunities. Mountains are also a place for spiritual sanctuaries and are often used for journeys of self-reflection through pilgrimage.

In addition to these ‘feel good’ benefits, mountains are hazardous areas for communities and infrastructure and are vulnerable to natural disasters. Mountainous areas are also often natural borders defining geopolitical entities, but in the process splitting and marginalising communities, creating economic shadow zones and sometimes becoming highly militarised areas. 

“Southern African mountains provide enormous opportunities for holistic research as social-ecological systems, with some of the most interesting and least academically explored environments on Earth,” said Dr Vincent Clark, Director: Afromontane Research Unit (ARU) on the UFS Qwaqwa Campus

The Afromontane Research Unit
The Qwaqwa Campus of the University of the Free State (UFS) is the home of the ARU, a multidisciplinary flagship group addressing the largely under-researched mountainous landscapes of southern Africa. 

Research in the ARU is promoted around three broad themes to foster inter- and multidisciplinary discourse: (1) conservation and sustainable use of Afromontane biodiversity; (2) sustainable futures for the people of the Afromontane; and (3) living and doing business in the Afromontane –  with the intention of creating a sustainability science hub to bring the three themes into the ambit of solution-oriented transdisciplinary research, centred in the sustainable development goals and sustainability research in general. 

Continental leader
To achieve its vision of becoming a continental leader in African mountain research, the ARU is positioning itself as a mountain-knowledge generator and interchange by developing key relationships locally and internationally. The most valuable local partnership is with the South African Environmental Observation Network (SAEON), with which the ARU will be sharing a Research Chair. 

The Chair will contain strong expertise in the Social Sciences to complement the existing strong Natural Science element in both the ARU and SAEON. The Sustainability Science component is being built through inter alia a mutually-reinforcing relationship with the University of Tokyo and United Nations University, Tokyo. 

The future
“In tandem with robust collaborations to achieve its goals, the ARU provides an envious capacity-building programme for its early career campus academics, postdoctoral and postgraduate students,” said Dr Clark. 

The scale of influence of the ARU is prioritised as ‘back yard first’, namely solution-oriented research that benefits Phuthaditjhaba, Qwaqwa, Golden Gate Highlands National Park and Royal Natal National Park. Thereafter, the ARU seeks to facilitate research that encourages the sustainable development of the Maloti-Drakensberg as a unique social-ecological system in Africa, and from there facilitate research in the intellectual vacuum that is the southern African mountains. With time, the ARU aims to take the intellectual lead as an Africa-based leader in African mountain research. The success of this will depend on how carefully the development of human infrastructure can be balanced with that of the myriad opportunities presented.”

With a diverse and motivated team, situated in one of the most attractive environments in Africa, the ARU is here to change the way we think about African mountains and what they mean for us all. 

News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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