Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
27 August 2018 Photo Sonia Small
Prof Thuli Madonsela persuades women to pursue their purpose
Discovering that she was “pretty” for her purpose gave Prof-Adv Thuli Madonsela’s life direction.

What does embracing womanhood mean? For Prof Thuli Madonsela it is about loving yourself and whatever you believe is your purpose in life. 

“All of us are designed for our purpose and are fit for our purpose, you should embrace that and make the best of it,” said South Africa’s former Public Protector in her keynote address to the Women’s Breakfast. In commemoration of Women’s Month, the University of the Free State (UFS)’s Employee Wellness Division hosted the annual event on 21 August 2018 where 900 women gathered under the theme: ‘Embrace your womanhood.’ 

Being a woman today


Law Professor and Law Trust Chair in Social Justice at Stellenbosch University, Prof Madonsela, urged the audience to look beyond the exterior and recognise “that we as individuals have a lot in common”. Speaking of unity in diversity, she praised some of the giants on whose shoulders modern women stand, such as Charlotte Maxeke, Olive Schreiner, Una Wookey, Albertina Sisulu, Winnie Madikizela-Mandela, Helen Joseph, Pam Golding, Bessie Head, and Ellen Khuzwayo.

These leaders are the epitome of following the purpose of “embracing everyone’s humanity and challenging things that diminish the humanity of others”, according to Prof Madonsela.

Remaining resilient and resolute 

Despite having to contend with a patriarchal system and face challenges such as gender-based violence, femicide, poverty, inequity, media stereotypes, as well as poverty, women continue to rise. Prof Madonsela called for women to capitalise on positives such as freedom and possessing a certain degree of power, legal equality, playing a role in political spaces, economic progress, and owning a public voice.

Drawing inspiration from her humble beginnings and the lessons learnt in leadership, Prof Madonsela conveyed a simple message to all women: “You are exactly as you should be. You are a perfect expression of your creator’s magnificence. You were created for a purpose and whatever you do, just step up and pursue your purpose.”

A word from an inspired woman

It was a memorable event for Burneline Kaars, Head of Employee Wellness. “This year it was an honour to host Prof Madonsela who could share both her academic background and professional experience. She accomplished this by skilfully incorporating lessons from our country’s history and her passion for justice,” she said.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept