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10 December 2018 | Story Leonie Bolleurs
Quantity Surveying
Winning national awards at the South African Council for the Quantity Surveying Profession’s 10th international research conference were, from the left: Prof Kahilu Kajimo-Shakantu with honours graduate student Melissa Moss, centre, and Mariska Karsten, a current honours student in Quantity Surveying and Construction Management.
Melissa Moss, a student from the Department of Quantity Surveying and Construction Management at the University of the Free State (UFS), has won the prestigious Association of South African Quantity Surveyors (ASAQS) Gold Medal Award 2018 for excellent performance at honours levels.

According to Prof Kailua Kajimo-Shakantu, the head of the department, this is an annual award which all institutions in South Africa that offer accredited Quantity Surveying programmes compete for. The adjudication process is undertaken by an independent panel consisting of several prominent academics as well as practitioners. The criteria for the award include; outstanding academic achievement and the individual’s involvement in extramural activities, contribution to community, social responsibility, personality and leadership qualities.

Aim for critical-thinking graduates

The achievement is in line with the department’s aim of developing, by means of dynamic scientific education, independent, critical-thinking, and well-rounded graduates who will become leaders in their field. 

Melissa, an honours student, received the premier award from ASAQS for excellent achievement over her four years of study.

The department is also very proud of Mariska Karsten. She was a runner-up for the ASAQS Future Leaders Award 2018 for excellent achievement over her three years of study. While the ASAQS Gold Medal Award has been in existence for decades, the ASAQS Future Leaders Award is a new category introduced in 2017 when the “inaugural” award was won by another of the UFS Department’s students, Gerné Bothma.

“Individuals such as these students of ours should be recognised, encouraged and nurtured so that they can reach their full potential and become the future leaders that not only the profession needs but also academia and the country as a whole. They are smart young people who show promise to contribute positively towards the profession. I have no doubt that they will serve the profession well with commitment, passion, integrity and creativity. I am proud of their achievements and the possibilities ahead of them,” said Prof Kailua Kajimo-Shakantu.

Both Melissa and Mariska received their national awards, presented this year at the 10th South African Council for the Quantity Surveying Profession (SACQSP) International Research Conference gala event held in Johannesburg. The conference was themed: The Quantity Surveying Profession and the Fourth Industrial Revolution.  

First female president of ASOCSA

Earlier this semester, Liane van Wyk, an honours student in Construction Management, presented and won the Best Student Research Proposal Competition Initiative at the 12th Built Environment Conference held in Durban. Liane, together with Prof Kajimo-Shakantu, and master’s student, Isabella Chandi, presented papers at the conference. 

A highlight for Kovsies at the conference was Prof Kajimo-Shakantu being elected and inaugurated as the sixth and first female President of the Association of Schools of Construction of Southern Africa (ASOCSA).

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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