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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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Qwaqwa Campus honours academic excellence
2017-05-18

Description: QQ autumn Graduation 2017 Tags: QQ autumn Graduation 2017

Photo: Ian van Straaten

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Qwaqwa Campus kicked off the 2017 graduations season of the University of the Free State in style when over 550 degrees and certificates were conferred in three sessions on 12 and 13 May 2017. These included five PhDs from the Faculty of Natural and Agricultural Sciences.

In his maiden speech delivered during the two ceremonies on Friday 12 May 2017, the newly-appointed Vice-Chancellor and Rector, Prof Francis Petersen, emphasised the interconnectedness of graduates with other stakeholders in their communities.

“Never forget the role played by other people who sacrificed a lot for you to be here today. Recognise the extra mile that someone was willing to go for you to graduate,” he said to an enthusiastic audience that included Grade 12 learners from neighbouring schools. 

Prof Petersen also reminded the graduates that not everybody had an opportunity to enter, enrol, and eventually graduate at a university. “You are part of the privileged few, and I am confident that the UFS has given you an equal opportunity to reach your full potential. You have had years of exposure to ideas and experiences on diversity. You now have the opportunity to show the world and to use what you have learnt beyond a classroom,” he added.

“Go out there and open doors for others as much as they were opened for you. I implore you to carry over your experiences of diversity and use them to build a better world. Go out there and build a better world, not only for yourself but for everyone in need. Expand your influence, reach out, and be accountable,” he said.

“South Africa needs your skills,
innovation, knowledge, expertise,
and creativity.”

Make your own unique contribution
The session held on Saturday 13 May 2017 saw the Principal of Motheo TVET College and Qwaqwa Campus alumnus, Dipiloane Phutsisi, having a heart to heart with the graduates from the Faculty of Education.

“Our contribution to the world as graduates will not be measured by the wealth we accumulate or the accolades we receive, but rather by the way in which we share our unique gifts with the world. And the only place to find those gifts is to look within yourself. As the class of 2017, make your own unique contribution,” she said.

“Your graduation takes place at a particularly challenging time in the history of our democracy. It happens at a time when our nation is engulfed by racial polarisation, anger, confusion about what democracy and freedom mean to us, and at a time when the pillars of morality are tested.”

“As you graduate, I wish to remind you that our country needs you more than ever before. South Africa needs your skills, innovation, knowledge, expertise, and creativity,” she said.

Three members of the current SRC were also among the graduates. They are the President, Njabulo Mwali (BSc Information Technology), Sports Affairs Officer, Ntokozo Thango (BA Sociology), and Student Development and Environmental Affairs Officer, Ntokozo Masiteng (BA Sociology).

 

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