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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

First-year wellbeing a top priority at Harmony residence
2017-06-07

Description:First-year wellbeing a top priority at Harmony residence Tags: First-year wellbeing a top priority at Harmony residence

Ladies from the House Harmony, a unique residence
that focuses on first-years’ experience.
Photo: Supplied

A unique residence that focuses on first-years’ experience, is exactly what Harmony sets out to provide for all first-year students at the University of the Free State.

A residence focusing on mentoring

Entering the adult world can be a daunting experience, but Harmony, unlike other residences on campus, focuses on mentoring. Harmony came to life in 2014 and has assisted many first-years in adapting to the university environment.

According to Pulane Malefane, Residence Head of House Harmony, they have witnessed a significant change in the pass rate of first-year students. “We have realised that first-years gain confidence much quicker than in other residences where they still need to find their way around seniors,” she says.

Adapting to the varsity environment

Harmony makes use of a Residence Assistants (RA) system, not Residence Committees (RC). The RA stay in corridors with their mentees in order to have close contact with them. An RA’s primary role is to be a mentor to first-years and also expose them to different co-curriculum activities on campus. They assist them in adapting to the varsity environment quicker, so as to be able to focus and concentrate on their academics.

Nicole Rabe, RA First-years, says the Harmony belles never cease to amaze her. “Watching these first-years grow from the high school girls that arrived at the start of this year, to the independent women they are now, has truly been a blessing.”

Malefane mentions that they intentionally try to place students from one faculty in the same corridor. In that way, mentors and residence assistants are in close proximity to them. “We have study rooms in each and every corridor of Harmony, making it easy for students to study close to their rooms at any time,” she says.

Phathutshodzo Nekhavanmbe, a first-year LLB student, says she could not have asked for a better house to be placed in. “The Harmony experience has been great so far, as the people living there are approachable and eager to lend a helping hand.”

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