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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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UV Voices Kamerkoor by die KKNK
2005-03-10

Membra Jesu nostri – Buxtehude (1637 – 1707)
 

Membra Jesu nostri patientis sanctissima (Die allerheilige liggaam van die lydende Jesus aan die kruis) deur Buxtehude het die Kruisiging van Jesus as tema.

Die uurlange werk word in Latyn gesing en handel in elk van die sewe dele oor ‘n deel van Jesus se liggaam aan die kruis: voete, knië, hande, die sy, bolyf, hart en gesig. Voices Inc – Kovsie kamerkoor word bygestaan deur die Odeion Strykkwartet met Francois Henkins, Abrie de Wet, John Wille en Michaela Haller. Die kontrabas word deur Alba Henkins-Molller bespeel en Jan Beukes is die orrelis.

Die woorde in Latyn wat buitengewoon was vir ‘n werk deur Buxtehude, is geneem uit die Latynse Bybel (Vulgate) en van die Rhytmica Oratio Sancti Bernadi, ‘n strofiese gedig deur St Bernard van Claivaux (c1090 – 1153).

Die wyse waarop Jesus se pyn aan die kruis uitgebeeld word asook die gebed en uitroep van versoening tussen God en die mensdom was deel van die Piëtiste se oortuigings van die tyd.

Die werk is saamgestel uit sewe afsonderlike dele wat telkens deur ‘n instrumentale sonate aangekondig word. Die koor lui die vokale bydrae in en sluit elke deel ook af. Die res van die werk bestaan uit verskillende groeperings van solo’s en trio’. Interessante vokale kombinasies kan gehoor word, bv. twee soprane en bas asook sopraan, alt en tenoor.

Hierdie opwindende aanbieding van Membra Jesu nostri, ‘n juweel uit die Baroktydperk, word aangebied deur ‘n groep energieke studente van Kovsies. Die jeugdige klank van die soliste – almal studente aan die Universiteit van die Vrystaat - dra by tot die egtheid van die Barok-klank. Die koor staan onder leiding van Leona Geldenhuys, dosent in Koorleiding aan die UV.

Optreedatums in die Moederkerk op Oudtshoorn. is:

 

  • Vrydag 25 Maart om 19:00
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