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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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The management teams of the University of the Free State and the Vista University Bloemfontein campus set the wheels rolling for the incorporation of
2003-05-22

The management teams of the University of the Free State and the Vista University Bloemfontein campus set the wheels rolling for the incorporation of the Vista Bloemfontein campus into the UFS.

The incorporation process will be dealt with in two phases. The first phase would be preparing for a possible incorporation on 1 January 2004, including possible streamlining and review of programmes. The second phase would be part of developing the long term vision or optimal reconfiguration of the Vista facility (within the UFS as a multi-campus institution) in the interests of higher education in the Free State and the communities surrounding the two campuses in Bloemfontein.

At a meeting at the UFS both parties reached consensus about the process and set about establishing task teams to deal with critical issues, such as governance and management, financial management, human resources, information systems, library services, student support and administration, academic planning and academic programmes.

Prof Talvin Schultz, Head of the Vista Bloemfontein campus, committed this campus to making the process of incorporation into the UFS an exemplary process. UFS Rector Prof Frederick Fourie said the Free State should continue its tradition as a province where things happen and where higher education transformation has proceeded faster than elsewhere in the country.

Both emphasised the need for an inclusive process of consultation with staff, students and the community on key aspects of the incorporation.

They indicated that all planning should take into account a possible date of incorporation of 1 January 2004, pending finalisation by the respective Councils. The Councils of both institutions need to give feedback to the Minister of Education on the date of incorporation by the end of June, and the task teams must deliver an initial report on progress before then.


Prof Talvin Schultz (Vista Bloemfontein campus) and Prof Frederick Fourie (UFS)

 

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