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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Inaugural lecture focuses on intercultural communication
2005-03-15

Prof Johann de Wet, chairperson of the University of the Free State’s (UFS) Department of Communication and Information Studies, will deliver his inaugural lecture on Wednesday 16 March 2005 at 19:00 in the CR Swart Auditorium on campus.

The topic of the presentation is Meeting on the “narrow ridge” in intercultural communication.

Prof de Wet obtained the BA degree in 1977 at from the University of Cape Town, in 1982 an honors degree cum laude in Journalism from the University of  Stellenbosch, in 1985 an MA degree from the University of South Africa (UNISA) and in 1987 the D Litt Et Phil, also from UNISA.

His earlier professional life included being a diplomat stationed in Washington DC, and a SABC journalist.

Prof de Wet’s first stint in the academe was at UNISA (1983-1993) and the UFS (1993-1995).  He was an associate professor at both institutions.  Before returning to the UFS in 2001, Prof de Wet was director of communication in the public service, ministerial spokesperson at national and provincial levels, contributing editor of the Cape Argus, and communication consultant for various public and private sector institutions.

In his academic career of 16 years, Prof de Wet has authored/edited 12 scholarly books.  His other research outputs include some 20 accredited articles and scientific papers (national and international) respectively.  Much of his research has focused on persuasive and political communication, journalism and general communication theory. 

He is the founding and current editor of Communitas, a nationally-accredited academic journal on community communication and information impact.  He was appointed professor and chairperson of the Department of Communication and Information Studies at the UFS in January 2004.

MEDIA RELEASE
Issued by: Lacea Loader
Media Representative
Tel:  (051) 401-2584
Cell:  083 645 2454
E-mail:  loaderl.stg@mail.uovs.ac.za
15 March 2005

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