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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

UFS celebrates Kovsie Week
2009-08-21

The University of the Free State (UFS) will be celebrating Kovsie Week from 31 August to 4 September 2009. The week affords friends, colleagues and former colleagues of the UFS the opportunity to enjoy one another’s company and to experience what the university offers.

The programme is as follows:

On Monday, 31 August 2009, a star-gazing programme and lecture entitled “400 Years of Astronomy after Galileo” are presented by Prof. Matie Hoffman at the Boyden Observatory at 17:30 for 18:00. Attendance is free and bus transport will be available from the UFS Main Campus for the first 70 guests that respond. Reserved parking has been arranged with a security guard to look after the cars that are left on the campus.

On Tuesday, 1 September 2009, guests can attend the production by Pieter Venter entitled “Impi” for free in the Wynand Mouton Theatre at 14:30 for 15:00.

On Wednesday, 2 September 2009, an enjoyable morning in the company of Mr Derek de Bruyn from the National Museum is presented at the Centenary Complex of the UFS at 09:30 for 10:00. He will talk about the social life of Bloemfontein during the early 1900s and guests will be entertained by the Boere Orkes of Grey College Primary School under the direction of Santjie Louw. Attendance of this event is free.

On Thursday, 3 September 2009, at 19:00 for 19:30, a candle-light, sherry and soup evening with romantic piano music is presented at the UFS Centenary Complex by Prof. Nicol Viljoen from the UFS’s Department of Music. The programme includes, amongst others, 10 Lieder ohne worte (Felix Mendelssohn), as well as Ballade No. 1 (Fryderyk Chopin). Attendance of this event is also free.

The week will end with the Kovsie-Alumni Award Gala Dinner that will take place in the UFS Centenary Complex on Friday, 4 September 2009, at 18:30 for 19:00.
The cost per person for the dinner is R120. The Kovsie of the Year Award for alumni, the Cum Laude Award, and the Alumni Award for Exceptional Service at the UFS will be awarded at this occasion.

Transport can be arranged to all the functions and parking will be available as close as possible to the venue where the functions take place. Persons interested to attend any of the functions can contact Annanda Calitz at 051 401 3382 or ficka.stg@ufs.ac.za, or Ms Kathy Verwey at 051 401 9343 or verweyke.stg@ufs.ac.za.

Media Release
Issued by: Lacea Loader
Deputy Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
21 August 2009

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