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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

UFS Centenary ends with a weekend of festivities
2005-02-04

The University of the Free State ’s (UFS) Centenary celebrations will come to an end this weekend with a packed programme.

“We celebrated this momentous milestone of the UFS since 28 January 2004 and want to end the year on a high note,” said Mr Jan Ras, Centenary Coordinator.

The weekend will start on Friday 4 February 2005 when Prof Frederick Fourie, Rector and Vice-Chancellor, will open the UFS officially. This will be followed by an historic photo of all staff and students who are on campus that day. All staff will be wearing their academic gowns and the Centenary emblem will be depicted.

The annual Kovsie Engen Rag, with We thank you South Africa as theme, will take place on Saturday 5 February 2005 . The procession will start at 08:00 from the UFS Kovsie church and will move down Nelson Mandela Drive and right into Markgraaff Street exit until it reaches St Andrew’s Street. From here it will turn right into Kings Way where it will stop at the Art Market at 10:00 . Prof Frederick Fourie will then propose a toast on the procession. Afterwards the groups and orchestras will step out and the floats will move through the center of town around Hoffman Square and then back to the UFS campus.

According to Mr Ras a reunion for the Student Representative Council (SRC) will also take place this weekend. About 100 former SRC members are expected to attend the planned activities.

The weekend will be concluded on Sunday 6 February 2005 with a special service of devotion, hosted by all the interdenominational groups on the campus. The service starts at 18:00 for 18:30 in front of the Main Building of the UFS and will be a celebration of praise, thanks and worship, followed by a message from Dr Wollie Grobler. The evening will be concluded with a mass choir and a fireworks display.

“Members of the public are welcome to attend the service of devotion and are requested to bring a candle for the purpose of the mass choir. Although chairs will be arranged in front of the Main Building , people are requested to bring extra pillows and blankets to sit on,” said Mr Ras.

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