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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Max du Preez on South Africa’s leadership vacuum
2011-08-29

 

Present at the CR Swart Memorial Lecture was, from the left: Prof. Hussein Solomon, senior Professor in our Department of Political Science; Prof. Theo Neethling, Head of our Department of Political Science; Max du Preez and Prof. Lucius Botes,Dean of our Faculty of Humanities.
Photo: Stephen Collett

“Much has been going wrong in South Africa in the last few years and it’s all due to a lack of strong, visionary leadership. South Africans deserve better and should demand more integrity, courage and vision from the present political leadership,” veteran journalist and author Max du Preez told the audience at a packed Wynand Mouton Theatre at our university, on 25 August 2011.

Delivering this year’s CR Swart Memorial Lecture on the topic “Of Jacob, Julius, Jimmy and the Dancing Monkey”, Du Preez told the audience to look with much more critical eyes at the political leadership and decide who is doing the obvious, following his or her basest instincts or simply trying to play to the gallery. “Why look at a man like Julius Malema and let him upset us, why listen to Floyd Shivambu with his crude manners and let them define us?” Du Preez asked the more than 300 people attending the memorial lecture. The CR Swart Memorial Lecture, the 41st hosted by the UFS, attracted one of the largest crowds ever for a public lecture, with some people sitting on the steps inside the auditorium of the Wynand theatre.
 
Telling the story of African philospher Morena Mohlomi, who acted as a teacher to Basuto king Moshoeshoe, Du Preez told the audience that the country needs counter-intuitive leadership like the two leaders had demonstrated. Calling Mohlomi southern Africa’s first Pan Africanist, Du Preez said the extroadinary thing about Morena Mohlomi and his student was their gift of counter-intuitive leadership, leadership that was daring and visionary, leadership that did not simply do the obvious. Pointing out other visionary leaders like Nelson Mandela, Oliver Tambo, Walter Sisulu, Beyers Naude and Van Zyl Slabbert, Du Preez urged the audience to question “the quality of leadership of Cosatu, the Democratic Teachers Union that is messing up our education, the Communist Party, the Democratic Alliance, the Freedom Front Plus and Solidarity. If they don’t live up to our expectations, why do we still tolerate them?” Du Preez asked.
 
Du Preez also commended Prof. Jonathan Jansen, Vice Chancellor and Rector of the UFS, for his counter-intuitive leadership regarding the Reitz Residence incident and said Prof. Jansen’s solution, as controversial as it was, brought a much better outcome.
 
Please find attached the full speech of Max Du Preez.

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