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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Albert Einstein “visits” Bloemfontein
2005-08-30

 

 

Albert Einstein, performed by David Muller, and Dr Matie Hoffman, senior lecturer from the Department of Physics at the UFS and coordinator of educational activities at the UFS Boyden Observatory.  They are standing at the 1,5m Boyden telescope.


Visitors to the University of the Free State’s (UFS) Boyden Observatory had a special treat on Saturday 27 August 2005 when they were “Albert Einstein”, alias David Muller (Albert Einstein in Imagining Einstein) paid them a surprise visit.

The Department of Science and Technology is sponsoring a one-man play called Imagining Einstein.  The play, written and performed by David Muller, is produced through the MTN Science Centre and forms part of the celebration of the World Year of Physics.  The play’s visit to Bloemfontein was kicked off by Saturday evening’s performance at the UFS Boyden Observatory.

It follows the life of Einstein, from his patent office in Switzerland, through his office in Berlin to his position at Princeton where he spent the last 20 years of his life and captures the research, studies and thinking with all its depth and insights of a man who not only changed the thinking about physics but also had much fun doing so.

The play will be presented on Tuesday 30 August 2005 and Wednesday 31 August 2005 at 10:00 and 19:00 in the Albert Wessels Auditorium on the UFS campus.  Entrance is free of charge.  For bookings, please contact (051) 401 2561.

On Thursday 1 September 2005 the play will be presented at 10:00 and 19:00 at the Sterrewag Theatre on Naval Hill.  Tickets are R10 per person for the 10:00 show and R30 per person for the 19:00 show and are available from PACOFS booking offices or by calling (051) 447 7772.   

Media release
Issued by:  Lacea Loader
   Media Representative
   Tel:  (051) 401-2584
   Cell:  083 645 2454
   E-mail:  loaderl.stg@mail.uovs.ac.za
29 August 2005
 

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