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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Senior leadership approves CSRC appeal
2012-05-14

The senior leadership of the UFS has approved the appeal lodged by the Central Student Representative Council (CSRC) to allow students deregistered on 30 April 2012 for not meeting their financial obligations, to write the May/June 2012 exams.
 
As from 14 May 2012, a relatively small number of 428 deregistered students will automatically have their registration reinstated and they will be granted the opportunity to write exams, provided that they have obtained a 40% predicate mark for each module.
 
A name list of the deregistered students will be sent to the heads of departments where they were enrolled. Only students who have obtained a 40% semester mark will be permitted to write exams.
 
Today the Executive Committee of Senate approved a recommendation that those students who only become aware of this arrangement after one of their scheduled modules has already been examined, may apply for permission to the Academic Timetables and Venues Office, Room 166, George du Toit Administration Building on the Bloemfontein Campus, to write a special examination. On the Qwaqwa Campus students may apply for permission to the Examination Section, Room 137 in the Administration Building.
 
This will, however, be a once-off opportunity and students will not be afforded another opportunity to write exams if they miss the first examination opportunity as well as the special examination. A student who writes only the special examination and fails will not be given a further opportunity. A student who writes the main examination and does poorly, but qualifies for a supplementary examination, may write the supplementary examination in the additional examination period.
 

This arrangement applies to all UFS campuses.
 

Media Release
14 May 2012
Issued by: Lacea Loader
Director: Strategic Communication
Tel: +27(0)51 401 2584
Cell: +27(0)83 645 2454
E-mail: news@ufs.ac.za

 

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