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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

University ready for 2013 registration process
2012-12-05

16 November 2012

Thousands of new first-year students are expected at the University of the Free State (UFS) in January 2013 and the University is ready to receive them. Everything is in place to allow the registration process to run smoothly for new, as well as senior students.

As in previous years, the Callie Human Centre will be the central point during the registration process. Students will get advice on registration, admission, academic programmes, class fees, residences and other information there.

New first-year students and their parents or guardians will be welcomed on the Qwaqwa Campus on 18 January 2013 and on the Bloemfontein Campus on 19 January 2013 by Prof. Jonathan Jansen, Vice-Chancellor and Rector. Four sessions are scheduled in which Prof. Jansen will spend time with new students of the different faculties on the Bloemfontein Campus. New first-year students will register from 21 to 25 January 2013.

Registration for senior students will commence on 14 January 2013. Those who do not live in university residences register from 14 to18 January 2013, while students who live in residences can register from 28 to 31 January 2013.

For further enquiries, contact the UFS Information Office on 051 401 3000. For more information on the registration process, visit our webpage and click on the heading More about us.

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