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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Multimillion rand donation to boost UFS schools
2013-02-05

At the launch were Dr Cobus van Breda, Director of the Science-for-the- Future Unit at the UFS, Mr Makhetha Botsane from the Free State Department of Education Mrs. Elizna Prinsloo, Programme Manager of the Family Maths and Family Science project and Mr Graham McCulloch, Free State representative of the Ilima Trust.
Photo: Kelly Abrahams
05 February 2013

The University of the Free State’s UFS) Family Maths and Family Science project has received a R1 million sponsorship from Old Mutual for 2013. This is a three-year project whereby the university’s School of Open Learning aims to demystify mathematics and science in the early school years, as stated in their mission. The launching ceremony took place on 1 February 2013 at the UFS Campus.

The sponsorship was made available by Old Mutual, but will be managed by the project management group, Ilima Trust.

The UFS received R30 million altogether from Old Mutual for the use on various projects.

Except for the Family Maths and Family Science project, the Schools make over project and the Internet Broadcasting Programme will also benefit from this donation.

“Ilima has a hands-on relationship with different projects and is the public face for the FM & FS sponsorship,” said Mr Graham McCulloch, Ilima Trust representative for the Free State.

“Today is the first step on the long road to improving math and science in the country,” McCulloch said.

Dr Cobus van Breda, Director of the Science-for-the-Future Unit  says the Family Math and Family Science Project makes science and math accessible to children and their parents in the early years, with the aim of developing positive attitudes towards these often difficult school subject.

“This project aims to empower educators, parents and student educators by iving support and training in hands-on teaching methodologies.”

Learners, educators and parents from 18 schools in Thaba Nchu and Botshabelo will benefit from this project. Teachers will receive training at the UFS and then return to their community to train parents and to teach learners. Teachers will also receive activity material to use in classrooms.

“The selection of the 18 participating schools took place by identifying feeder schools of secondary schools from the UFS School Change Project, trying to create a whole-school development,” Van Breda said.

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