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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Learners to benefit from UFS Partnership for academic excellence
2013-02-21

 

Thokoana Makaota learners listening attentively during the launch of the partnership with the UFS.
Photo: Thabo Kessah
21 February 2013

The university’s quest for academic excellence in the education system paved the way for the Faculty of Education on the Qwaqwa Campus to enter into a mutually beneficial partnership with a local school, Thokoana Makaota Secondary.

This recently launched partnership will enable learners who are currently in grades 10-12 to attend supplementary classes on the campus.

“The aim of this partnership is to expose learners from the school to adequate tuition in subjects that are generally perceived as difficult. We want them to gain as much confidence as possible when tackling these subjects, therefore they will be using our well-equipped laboratories and classes”, said Dr Lekhooe Letsie, the Programme Coordinator.

“We will also benefit from this as our own final-year education students will act as tutors. This will help them gain confidence before they venture into the real job market next year,” Dr Letsie said.

Dr Letsie also revealed that the student-teachers will be closely monitored by their mentors to ensure maximum success.

The school’s Deputy Principal and UFS alumnus, Serame Sello, said that the school felt humbled by this gesture from the UFS.

“We are confident that this working relationship will yield very positive results for the school and enable us to improve on the 84% pass rate obtained in 2012,” Sello said.

“We did not do so well in the subjects that will be covered here. For instance, we obtained 43% and 61% in Physical Science and Mathematics respectively, but with this partnership we hope for improved results this year,” said Sello.

Other subjects to be covered include Geography, Life Sciences, Economics, and Accounting. The different grades will commute to and from campus on different afternoons.

 

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