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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Strong support for march against gender violence
2013-02-27

 

A huge group of students, led by the Student Representative Council, took part in the "Enough is Enough: Are you man Enough?" march on the Bloemfontein Campus.
Photo: Johan Roux
25 February 2013

   YouTube Video: "Enough is Enough" Harlem shake

   YouTube Video: "Enough is Enough" protest

Enough is enough. The UFS took a vocal and visual stand against gender violence and rape with a march joining the national protest movement. With banners reading: ‘No to rape,’ ‘Stop sexual terrorism’ and ‘Enough is enough’, hundreds of Kovsie men and women took part in the Enough is Enough: Are you man Enough march held on the Bloemfontein Campus. Led by Mr Rudi Buys, Dean of Student Affairs, staff and students, mostly men, told the world what they think about the scourge of violence and rape in the country.

Addressing protestors, Prof Jonathan Jansen, Vice-Chancellor and Rector, highlighted shocking rape statistics, saying that it is dangerous to be a woman these days with a woman raped every minute somewhere in the country. “Women can hardly breathe without being worried.Culture has deceived our young men. The country is experiencing a tragic time. We need to raise our children, mostly boys, to respect women from an early age. They must also learn how to deal with their emotions – boys must learn how to cry.”

Joining Prof Jansen on stage was the Student Representative Council (SRC) presidents of three universities in South Africa – William Clayton from the UFS, Horne Hallendorff from the University of Cape Town and Clinton du Preez from Stellenbosch University. “Enough is indeed enough and men should take their role seriously to ensure that we say NO to gender violence and rape against women,” Clinton told protestors.

At the request of the Dean of Student Affairs, all the men that were present kneeled as a sign of apology of the selfish acts of men against women.

The university will continue the fight against gender violence with a series of dialogues creating awareness, but also facilitating broader understanding of gender violence.

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