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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Student leaders' hard work rewarded
2013-05-01

Four student leaders on our Bloemfontein and Qwaqwa Campuses each received a scholarship of R15 000. Handré Hay, Estine Cronje, Tsepang Lenka and Jean Vermaas were rewarded for the positive impact they had on the student community in the past three years or more. Student Affairs' scholarship programme acknowledges the contribution of student leaders in the upliftment of the student community.

Read what the four have to say about leadership:

Handré Hay:

Handré Hay, a third-year BSc Physiotherapy student who holds several leadership positions on our Bloemfontein Campus, served for two consecutive years on the committee of Armentum residence. He was also a member of the executive council in the Students' Representative Council (SRC) and served in two SRC portfolios. "Leadership is about being able to serve. When people see that you are willing to put other people's interests above your own and that you are willing to serve unselfishly, despite a position of authority, you will get far," said Handré.

Estine Cronje:

Estine Cronje is the current prime of Marjolein residence. This was the second time the fifth-year Psychology student were re-elected to this position."Leadership is very important to me. One needs leaders in everything you do. I believe a leader should never think herself better than the rest and should work as hard as her team. She should command respect, be disciplined, an example to others, accessible and open to the opinions of other people.

Tsepang Lenka:

Tsepang Lenka is the SRC President of our Qwaqwa Campus. Tsepang, who was twice elected as prime of his residence, has already obtained his BA degree in Public and Business Management. He is currently working on his Postgraduate Certificate in Education (PGCE). "To me leadership means to serve. As a leader you don't lie to people when things are taking the wrong direction, you stand firm and tell the truth; in that way, people don't lose trust in you. The scholarship inspires me to work even harder," Tsepang said.

Jean Vermaas:

Jean Vermaas is a former SRC member who is currently studying for his LLB degree. Some of Jean's achievements include leadership positions of the Juridical Society and the Broad Students' Transformation Forum. In 2012 he was a founder member of the Student Elders' Council."Leadership is of extreme importance to me. It formed me into the person I am now. Leadership isn't always easy, but in the challenges you face you grow as a leader and as an individual."

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