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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Goodbye SIFE, hello Enactus
2013-05-01

The Kovsies Enactus team
24 May 2013
Photo: Linda Fekisi

The Students in Free Enterprise, better known as SIFE, has changed its brand name to Enactus. This global rebranding took place late last year. It forms part of an attempt to increase the organisation’s level of reach and impact. It reflects that entrepreneurial action is not something that is relevant to a single culture or nationality.

The organisation is still in essence one which assists university students to create community empowerment projects. The Kovsies Enactus team has 53 active members on the Bloemfontein Campus.

“We encourage student development through Enactus. It is a great platform for students. There is a combination of ideas, expertise and diversity from different faculties,” says the Vice-Chairperson of internal affairs, Mirriam Matsoaboli.

Enactus is currently working on three major projects: Local Economic Development (LED) and Edcon, Shifting Focus, and an environmental project. LED works with 19 established businesses which are struggling to make a profit while Edcon deals with three designers in textile and clothes making. Shifting Focus forms part of the educational division. It focuses on instilling entrepreneurial skills in high school learners. The Enactus team serves as a mentoring structure and advises them. The environmental project is in its infant stage, with. Enactus working on recycling bottles and paper, especially old study guides on campus.

“Having a branch on the QwaQwa campus has also been one of our objectives. We are still in the process of establishing one,” adds Mirriam.

The Enactus team is currently preparing for the national competitions which will take place later in Sandton on 10 and 11 July.

  • Students tell us about your association and we will profile it on our Kovsielife page. Contact Amanda Tongha at tonghaa@ufs.ac.za

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