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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

Degree in Forensic Science for 2014
2013-08-16

16 August 2013

A BSc degree in Forensic Science will be presented for the first time at the University of the Free State (UFS) from 2014. It is also the first degree of its kind to be presented in South Africa.

According to the Department of Genetics in the Faculty of Natural and Agricultural Sciences the three-year degree is, among others, aimed at people working on crime scenes and on criminal cases in the SA Police Service and in forensic laboratories. At postgraduate level, students can specialise in a variety of forensic fields up to PhD.

A maximum of 80 students will be selected for admission to the course in 2014. Entrance requirements are an admission point of at least 34, as well as a combined minimum point of 17 for Mathematics, Life Sciences and Physical Science. Applications for 2014 close on 30 September 2013. About 700 to 800 new appointments were advertised in this field by the SAPS in the past two years.

The UFS has been offering an honours programme in Forensic Genetics since 2010.

The new course comes at a time when the Government is taking significant steps to eradicate crime in South Africa. At the first conference of the SA Police Service’s National Forensic Service in July 2013, it was reported that milliards of rand are spent to establish an integrated, modernised, well-manned and well-managed criminal justice system. New laboratories are already operational and more laboratories are planned, including one in each province.

The so-called DNA Bill is likely to be approved by Parliament before the end of 2013. Under this bill, all current schedule-1 criminals and suspected criminals will be obliged to provide DNA samples. This information will be stored in a DNA database.

According to the SAPS’ Serial Unit, approximately 1 300 serial killers are currently active in South Africa and the DNA database can be helpful to bring these and other criminals to book. About 80% of all crimes are committed by about 20% of the criminals.

More information on the Forensic Science degree can be found at forensics@ufs.ac.za or +27(0)51 401 9680 or +27(0)51 401 2776.

 

Issued by: Lacea Loader
Director: Strategic Communication

Telephone: +27 (0) 51 401 2584
Cellphone: +27 (0) 83 645 2454
E-mail: news@ufs.ac.za

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