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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

“Leisure can be of great geographical importance”
2013-09-26

 

Prof Gustav Etienne Visser
Photo: Supplied
26 September 2013
 

Prof Gustav Etienne Visser (43) is Professor in Human Geography at the University of the Free State. He has been with the university’s Geography Department since January 2002 and became a full professor in 2009.
Visser completed his MA in Geographical Research at the Stellenbosch University in 1996 and finished his PhD in Geography at the London School of Economics and Political Science in 2000. His thesis was titled: Spatialities of social justice: reflections on South African Cities.

Visser was a Post-doctoral Fellow at the School of Geography, Archaeology and Environmental Studies at the University of the Witwatersrand before his appointment at the UFS. He now teaches Urban Geography to third-year students and Tourism and Development to MA students.

His research interests so far have been Identity-based consumption and urban morphological change, Tourism and development nexus and Critical reflections on South African Geographical Research.

Visser’s publications summary is as follows:

- Four books – edited collections
- 28 book chapters
- 71 refereed articles
- Nine academic commentaries and research notes
- 14 research reports
- and 38 conference papers

His latest research on how people’s leisure time influences our urban spaces, is fundamentally relevant to everyday life.

“We tend to forget to think about it, but how people spend their leisure time is part of their lifestyle,” says Visser.“ And our urban surroundings are influenced by the lifestyles of its inhabitants.”

When asked about his own leisure time and activities, Visser humorously responds “There is no such thing.”

However, he is passionate about eating, cooking and wine.
“I must also watch a series every day – Dexter is definitely my favourite.
“Furthermore, I also travel abroad for about three months of the year, which is mainly for my research concerning urban spaces.”

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