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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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Kovsie archer aims for 2016 Olympics
2014-04-24


Sariça Coetzee

For some of us, archery is just something we see on film and television, like in the Hunger Games movies or on the Arrow TV series. Sariça Coetzee, a first-year BA Psychology and Criminology student, however, is almost like South Africa’s very own Katniss Everdeen.

Sariça recently won two gold medals in the division for Junior Women at the South African National Archery Association’s (SANAA’s) National Archery Championships. With the qualifying heats taking place next year, the Olympic Games of 2016, which is just around the corner, is beckoning her.

“I am working hard to get there and would love to go,” says Sariça.

“I train on a regular basis with Riaan Schoeman from Kovsies’ Exercise and Sport Sciences, in order to improve my technique and strength.”

Sariça’s training includes shooting at targets and spending time in the gym.

“I spend about three hours per day, four days a week, on training. In archery it is crucial to be able to keep your body stable when the wind is blowing.”

Sariça, who matriculated at Sentraal High School in Bloemfontein, stared with archery seven years ago.

“We drove past Old Grey’s archery club and I just wanted to do it as well,” she says.

“I begged my parents for almost a year to let me do it. They thought it was just a passing fancy, but I really developed a passion for the sport and had a feeling for archery from the beginning.”

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