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Research possibilities of zebrafish exposed

24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Pres Steyn turns pink in anticipation of Vryfees

2014-06-06

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Live streaming

Australian artist Cigdem Aydemir vacuum packed the Pres Steyn monument on the Bloemfontein Campus’s Red Plain – in pink. Aydemir’s project, ‘Plastic Histories’, forms part of a public art project that encourages us to evaluate public monuments in their historical context.

By vacuum packing monuments, Aydemir alludes to their significance and preservation. At the same time, though, it reveals the nature of their contentious and gendered historical function. This is because most monuments in post-colonial countries typically celebrate men’s achievements in serving their nations.

In response, this project acknowledges the contribution of women from all races, communities and sexual orientations to the grand narrative of a post-apartheid South Africa.

Aydemir is also developing an app in collaboration with Australian artist Warren Armstrong. This will be used for augmented reality viewing of three city monuments – those of President Brand, General De Wet and General Hertzog. This means that visitors will be able to hold a smart phone or iPad in front of the monuments and view the monuments as if vacuum packed in pink plastic.

In conjunction with the public art project there will be an exhibition of digitally manipulated photographs of nineteen-century and contemporary male monuments in Bloemfontein. These photos will be exhibited at the Johannes Stegmann Gallery at the UFS Sasol Library from 15 July – 1 August 2014.

Public tours on the Bloemfontein Campus and into the city will take place on:

• Tuesday 15 July at 11:00,
• Wednesday 16 July at 14:00, and
• Saturday 19 July at 11:00.

Aydemir’s ‘Plastic Histories’ public art project is part of the UFS Programme for Innovation in Artform Development (PIAD) and the Vryfees arts festival’s partnership with the Australian-based SituateArt in Festivals initiative. This partnership is managed by the Salamanca Arts Centre in Tasmania.