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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

New SANRAL Chair in Science, Mathematics and Technology Education
2014-09-19

 

MEC: Butana Khomphela
Photo: Jerry Mokoroane

The University of the Free State (UFS) in partnership with the South African National Roads Agency launched the SANRAL Chair in Science, Mathematics and Technology Education on the Bloemfontein Campus on 11 September 2014. Prof Loyiso Jita has been appointed as the first SANRAL Chair. He is a professor in the School of Mathematics, Natural Sciences and Technology at the UFS, where he shares his expertise in science teaching, which has been influenced by his broad and deep intellectual and experiential engagements both internationally and domestically.

Speaking at the event were Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS; Dr Choice Makhetha, Vice-Rector: External Relations; Prof Jita, the inaugural SANRAL Chair; the Free State MEC for Police, Roads and Transport, Mr Butana Komphela and Mr Nazir Alli, CEO of SANRAL.

At the event, Prof Jansen celebrated that “SANRAL has rewarded the faith in our children to do well in science and mathematics with this Chair.”

This SANRAL Chair in Science, Mathematics and Technology Education will help to improve the quality of teaching in these vital subjects at schools in the province. It complements the university’s School Partnership Project (SPP) – a flagship initiative launched by Prof Jansen.

The SANRAL endowment will enable the university to hone in on the ‘gateway subjects’ of mathematics and natural science. At school level, it will help to train teachers, support student-teacher interns, and incentivise education results so that participating schools become centres of excellence. At an academic level, the SANRAL Chair will supervise a cohort of doctoral and masters students, while also guiding research and publications in mathematics, science and technology education.

Through the endowment, SANRAL will assist the UFS in producing education leaders who can turn around maths and science education in disadvantaged schools throughout Southern Africa.

For the full text, read: New SANRAL Chair in Science, Mathematics and Technology Education

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