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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.
The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

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News Archive

The UFS #FaceOfFacebook
2014-11-14

At the UFS, we are committed to our Human Project, which sets the standard for good behaviour and care. It reaches internally to our students and externally to our prospective students and our communities.

And so, the Kovsies #FaceOfFacebook was born from the need to communicate with students and thus become a virtual friend. Yearly auditions are held to choose the new face representing the UFS on Facebook. The successful candidate holds the title #FaceOfFacebook for the next 12 months, attending events and filming short video clips to post on our Facebook page.

We had a quick chat with our current #FaceOfFacebook, Katleho 'Blue' Letube …

Who is Blue?

"Media mistress, fashion phenom, diva divine darling, superwoman and lover of life.
I was born in a small town called Bothaville, where my mom and her side of the family are living . I started pre-school there, moved and completed my schooling career at St. Andrew's High School (a very proud S aint) in Welkom. That is where my dad and his side of the family are living . Also, I am a proud resident of House NJ vd Merwe and I am studying Governance and Political Transformation."

How do you balance everything you do?

"It's relatively easy for me to strike a balance between my academics, social life and leadership duties, because Jesus is at the centre of all that I do. He is my guide and my strength. However, I also take it upon myself to prioritise. Although I am a '' liker of things'' , I ensure that my academics are the priority and everything else falls into place perfectly."

Are you dating someone?

"Hahaha, wouldn't you just love to know? Well, yes I am off-market. I'm completely taken and I'm happy."

What drives you?

"I always feel the urge to expand myself by working harder, smarter, stronger, and more efficiently. If there's an extra mile to go, the strength inside me draws out the willingness and ability to go that extra mile."

What is it like being the #FaceOfFacebook?

"I have been privileged to be entrusted with this duty and I carry it out with pride and passion. Being the #FaceOfFacebook means you get to meet a new face on campus almost every day, because people recognis e you and want to know you better. This opportunity has opened many doors for me and has equipped me with skills that have allowed me to grow as an individual. Therefore I will forever be grateful."

Where are you going to be in five years from now?

"Five years from now I would like to see myself as a better person both personally and professionally, in a respectable and reputed position earned through my hard work and skills. However, do not be surprised if you see me as a presenter on Vuzu.TV."

Advice to prospective students?

"Do not be that pupil who enrolled at this awesome institute and never takes advantage of its kindness. The University of The Free State is an institution that offers an excessive amount of opportunities to students. Step up and get out of your comfort zone. See an opportunity, seek the opportunity and cease it. You are at a university that provides you with a platform for you to grow."

What's your favourite colour?

My favourite colours are Black, White and Blue – hahaha!!

Kovsies can keep in touch:

Facebook: Katlego Blue Letube
Twitter: @Princess_blue31
Instagram: katlegoletube

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