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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Bloemfontein Campus hosts annual HELTASA conference
2014-12-09

 

From the left are: Prof Francois Strydom, Director: Academic - Centre for Teaching and Learning, UFS; Dr Lis Lange, Vice-Rector: Academic, UFS; and Prof George Kuh, Adjunct Research Professor of Education Policy at the University of Illinois.

This year, the privilege to host the annual Higher Education Learning and Teaching Association of Southern Africa (HELTASA) conference was afforded to our university. The event took place on the Bloemfontein Campus from 18 – 21 November 2014, attracting keynote speakers and members from across the world.

HELTASA is a professional association mainly for educators and significant role players in higher education institutions. With its inception in the early 2000s, it has grown to become the premier organisation for teaching and learning in Southern Africa, Dr Amanda Hlengwa, President of HELTASA, pointed out.

A central concern of this body is issues around success within the tertiary sector. The theme of this year, ‘Accessing success: using evidence for change’ served to focus members’ attention on what works and what does not work – as derived from researched evidence.

In a message from Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), he stressed that the task as university teachers “is not simply cognitive gains that ensure graduation success but also intellectual gains that ensure success in life during and after university studies.”

The conference was led by internationally-acclaimed keynote speakers, namely Prof George Kuh, Prof William Grabe and Prof Fredricka Stoller, as well as our own A1 NRF-rated Prof Malanie Walker.

Prof Kuh is Adjunct Research Professor of Education Policy at the University of Illinois and Chancellor’s Professor of Higher Education Emeritus at Indiana University. In his keynote address, Prof Kuh offered valuable lessons from the field to promote student success.

Profs Grabe and Stoller collectively presented the second keynote address that explored how to set up students for success through strategic-reader training. Prof Grabe is Regents’ Professor of Applied Linguistics and Vice President for Research at Northern Arizona University. Prof Stoller is a Professor of English at Northern Arizona University, where she teaches in the MA-TESL and PhD in Applied Linguistics programmes.

Prof Walker is a Senior Research Professor at the UFS Centre for Research on Higher Education and Development (CRHED). She is also currently Director of Research Training and a senior researcher in the EU-funded Marie Curie EDUWEL project. In her keynote address, Prof Walker looked at well-being and agency in higher education.

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