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24 December 2018 | Story Leonie Bolleurs | Photo Anja Aucamp
Research possibilities of zebrafish exposed
Leading global genetics laboratories are replacing research on human and animal populations with zebrafish, says Prof Paul Grobler, Head of the UFS Department of Genetics.

The UFS Department of Genetics is on par with current research trends in terms of their zebrafish project. About a year has passed since they seriously started focusing on the potential of this tiny four-centimetre-long fish, and the possibilities are hugely exciting.

Looks are deceiving

Leading global genetics laboratories are replacing research on human and animal populations with zebrafish due to several fascinating reasons, of which the most profound is probably that the zebrafish share large portions of its genome with mammals. For genetics researchers this may make a lot of sense, but most people battle to see any resemblance between a six-foot-tall rugby player or 600 kg buffalo and a small, nearly transparent fish. It is in the detail, the researchers say.

Fast, effective, and visible

“The complete genome sequence of the zebrafish is known, and as much as 84% of genes known to be associated with human disease have zebrafish counterparts,” explains Head of Department, Prof Paul Grobler. Another advantage is the fast breeding rate and short generation time, and the fact that some research is ethically more justifiable when done on fish larvae rather than on adult mammals. The fact that zebrafish embryos are virtually transparent, also allow researchers to examine the development of internal structures without effort. Every blood vessel in a living zebrafish embryo is visible under a low-power microscope.

Multidisciplinary

Zebrafish provide research potential for many different study fields besides that of Prof Grobler and his team, Sue Rica Schneider and Dr Willem Coetzer. In the near future, they aim to have undergraduate students use zebrafish as a research model to develop a real sense of research and laboratory work. The Department of Chemistry are also initiating research on zebrafish housed in the Department of Genetics.

News Archive

Splendid Summer Graduation concludes 2014 ceremonies
2014-12-11

  • Photo Gallery Afternoon session;  Morning session
  • YouTube

On Thursday 11 December 2014, the university awarded a total of 392 qualifications during our Summer Graduation Ceremony in the Callie Human Centre on the Bloemfontein Campus. Of these, 225 were awarded to graduates from the Faculty of Health Sciences, while 134 master’s degrees and 33 PhDs were awarded in the other six faculties. Another 74 diplomas and 56 certificates were also awarded in the School for Open Learning.

Well-known radio personality, Redi Thlabi, and acclaimed cardiothoracic surgeon, Dr Susan Vosloo, encouraged and inspired the graduates during the two ceremonies on the day.

During the morning session, Thlabi imparted some of the valuable lessons she learned in her personal life as well as in her career. She encouraged graduates to change the script of our country for future generations, to be mindful of others and to find meaning in whatever you do.

“Those who have a platform, a voice and an education have the power to help others further on their journey,” Thlabi said. “I believe we are living in an exciting time – a time to leave a legacy behind, a time to make a mark in this world.”

Graduates from the Faculty of Health Sciences and the School for Open Learning were addressed by Dr Vosloo during the second ceremony.

Dr Vosloo often referred to the success of transformation at our university and added that few successes are achieved without adversity. She encouraged the afternoon’s graduates to become professionals with a high sense of dignity, accountability and transparency in their workplace.

“Remember that you and you alone are able to decide what your approach will be in anything in life from here on forward,” she said.

Dr Vosloo, a Kovsie alumnus, graduated in 1980. Shortly after this, she became the first female heart surgeon in South Africa. She is currently in independent private practice at Christiaan Barnard Memorial Hospital, having also worked from 1998 untill 2012 at the Vincent Pallotti Hospital in Cape Town.

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